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The proteasome controls ESCRT-III-mediated cell division in an archaeon.
Tarrason Risa G, Hurtig F, Bray S, Hafner AE, Harker-Kirschneck L, Faull P, Davis C, Papatziamou D, Mutavchiev DR, Fan C, Meneguello L, Arashiro Pulschen A, Dey G, Culley S, Kilkenny M, Souza DP, Pellegrini L, de Bruin RAM, Henriques R, Snijders AP, Šarić A, Lindås AC, Robinson NP, Baum B. Tarrason Risa G, et al. Among authors: de bruin ram. Science. 2020 Aug 7;369(6504):eaaz2532. doi: 10.1126/science.aaz2532. Science. 2020. PMID: 32764038 Free PMC article.
Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition.
Wilson GA, Vuina K, Sava G, Huard C, Meneguello L, Coulombe-Huntington J, Bertomeu T, Maizels RJ, Lauring J, Kriston-Vizi J, Tyers M, Ali S, Bertoli C, de Bruin RAM. Wilson GA, et al. Among authors: de bruin ram. Mol Cell. 2023 Nov 16;83(22):4078-4092.e6. doi: 10.1016/j.molcel.2023.10.017. Epub 2023 Nov 16. Mol Cell. 2023. PMID: 37977119 Free article.
A ferrocene-containing nucleoside analogue targets DNA replication in pancreatic cancer cells.
Rana M, Perotti A, Bisset LM, Smith JD, Lamden E, Khan Z, Ismail MK, Ellis K, Armstrong KA, Hodder SL, Bertoli C, Meneguello L, de Bruin RAM, Morris JR, Romero-Canelon I, Tucker JHR, Hodges NJ. Rana M, et al. Among authors: de bruin ram. Metallomics. 2022 Jul 25;14(7):mfac041. doi: 10.1093/mtomcs/mfac041. Metallomics. 2022. PMID: 35689667 Free PMC article.
Cell cycle control in cancer.
Matthews HK, Bertoli C, de Bruin RAM. Matthews HK, et al. Among authors: de bruin ram. Nat Rev Mol Cell Biol. 2022 Jan;23(1):74-88. doi: 10.1038/s41580-021-00404-3. Epub 2021 Sep 10. Nat Rev Mol Cell Biol. 2022. PMID: 34508254 Review.
41 results