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A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy.
Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari SR, Mitchell K, Lopez A, Margulets V, Scarlata M, Santulli G, Asnani A, Peterson RT, Hazan RB, Condeelis JS, Oktay MH, Steidl U, Kirshenbaum LA, Gavathiotis E, Kitsis RN. Amgalan D, et al. Among authors: asnani a. Nat Cancer. 2020 Mar;1(3):315-328. doi: 10.1038/s43018-020-0039-1. Epub 2020 Mar 2. Nat Cancer. 2020. PMID: 32776015 Free PMC article.
Cyp1 Inhibition Prevents Doxorubicin-Induced Cardiomyopathy in a Zebrafish Heart-Failure Model.
Lam PY, Kutchukian P, Anand R, Imbriglio J, Andrews C, Padilla H, Vohra A, Lane S, Parker DL Jr, Cornella Taracido I, Johns DG, Beerens M, MacRae CA, Caldwell JP, Sorota S, Asnani A, Peterson RT. Lam PY, et al. Among authors: asnani a. Chembiochem. 2020 Jul 1;21(13):1905-1910. doi: 10.1002/cbic.201900741. Epub 2020 Mar 6. Chembiochem. 2020. PMID: 32003101 Free PMC article.
Circulating hemopexin modulates anthracycline cardiac toxicity in patients and in mice.
Liu J, Lane S, Lall R, Russo M, Farrell L, Debreli Coskun M, Curtin C, Araujo-Gutierrez R, Scherrer-Crosbie M, Trachtenberg BH, Kim J, Tolosano E, Ghigo A, Gerszten RE, Asnani A. Liu J, et al. Among authors: asnani a. Sci Adv. 2022 Dec 23;8(51):eadc9245. doi: 10.1126/sciadv.adc9245. Epub 2022 Dec 23. Sci Adv. 2022. PMID: 36563141 Free PMC article.
Priorities in Cardio-Oncology Basic and Translational Science: GCOS 2023 Symposium Proceedings: JACC: CardioOncology State-of-the-Art Review.
Salloum FN, Tocchetti CG, Ameri P, Ardehali H, Asnani A, de Boer RA, Burridge P, Cabrera JÁ, de Castro J, Córdoba R, Costa A, Dent S, Engelbertsen D, Fernández-Velasco M, Fradley M, Fuster JJ, Galán-Arriola C, García-Lunar I, Ghigo A, González-Neira A, Hirsch E, Ibáñez B, Kitsis RN, Konety S, Lyon AR, Martin P, Mauro AG, Mazo Vega MM, Meijers WC, Neilan TG, Rassaf T, Ricke-Hoch M, Sepulveda P, Thavendiranathan P, van der Meer P, Fuster V, Ky B, López-Fernández T; International Cardio-Oncology Society. Salloum FN, et al. Among authors: asnani a. JACC CardioOncol. 2023 Sep 27;5(6):715-731. doi: 10.1016/j.jaccao.2023.08.003. eCollection 2023 Dec. JACC CardioOncol. 2023. PMID: 38205010 Free PMC article. Review.
71 results