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A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy.
Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari SR, Mitchell K, Lopez A, Margulets V, Scarlata M, Santulli G, Asnani A, Peterson RT, Hazan RB, Condeelis JS, Oktay MH, Steidl U, Kirshenbaum LA, Gavathiotis E, Kitsis RN. Amgalan D, et al. Among authors: hazan rb. Nat Cancer. 2020 Mar;1(3):315-328. doi: 10.1038/s43018-020-0039-1. Epub 2020 Mar 2. Nat Cancer. 2020. PMID: 32776015 Free PMC article.
Loss of retinal cadherin facilitates mammary tumor progression and metastasis.
Agiostratidou G, Li M, Suyama K, Badano I, Keren R, Chung S, Anzovino A, Hulit J, Qian B, Bouzahzah B, Eugenin E, Loudig O, Phillips GR, Locker J, Hazan RB. Agiostratidou G, et al. Among authors: hazan rb. Cancer Res. 2009 Jun 15;69(12):5030-8. doi: 10.1158/0008-5472.CAN-08-4007. Epub 2009 Jun 2. Cancer Res. 2009. PMID: 19491271 Free PMC article.
Slug promotes survival during metastasis through suppression of Puma-mediated apoptosis.
Kim S, Yao J, Suyama K, Qian X, Qian BZ, Bandyopadhyay S, Loudig O, De Leon-Rodriguez C, Zhou ZN, Segall J, Macian F, Norton L, Hazan RB. Kim S, et al. Among authors: hazan rb. Cancer Res. 2014 Jul 15;74(14):3695-706. doi: 10.1158/0008-5472.CAN-13-2591. Epub 2014 May 15. Cancer Res. 2014. PMID: 24830722 Free PMC article.
Redox signaling by glutathione peroxidase 2 links vascular modulation to metabolic plasticity of breast cancer.
Ren Z, Liang H, Galbo PM Jr, Dharmaratne M, Kulkarni AS, Fard AT, Aoun ML, Martinez-Lopez N, Suyama K, Benard O, Zheng W, Liu Y, Albanese J, Zheng D, Mar JC, Singh R, Prystowsky MB, Norton L, Hazan RB. Ren Z, et al. Among authors: hazan rb. Proc Natl Acad Sci U S A. 2022 Feb 22;119(8):e2107266119. doi: 10.1073/pnas.2107266119. Proc Natl Acad Sci U S A. 2022. PMID: 35193955 Free PMC article.
35 results