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A small-molecule allosteric inhibitor of BAX protects against doxorubicin-induced cardiomyopathy.
Amgalan D, Garner TP, Pekson R, Jia XF, Yanamandala M, Paulino V, Liang FG, Corbalan JJ, Lee J, Chen Y, Karagiannis GS, Sanchez LR, Liang H, Narayanagari SR, Mitchell K, Lopez A, Margulets V, Scarlata M, Santulli G, Asnani A, Peterson RT, Hazan RB, Condeelis JS, Oktay MH, Steidl U, Kirshenbaum LA, Gavathiotis E, Kitsis RN. Amgalan D, et al. Among authors: santulli g. Nat Cancer. 2020 Mar;1(3):315-328. doi: 10.1038/s43018-020-0039-1. Epub 2020 Mar 2. Nat Cancer. 2020. PMID: 32776015 Free PMC article.
Infiltrating macrophages amplify doxorubicin-induced cardiac damage: role of catecholamines.
Gambardella J, Santulli G, Fiordelisi A, Cerasuolo FA, Wang X, Prevete N, Sommella E, Avvisato R, Buonaiuto A, Altobelli GG, Rinaldi L, Chiuso F, Feliciello A, Dal Piaz F, Campiglia P, Ciccarelli M, Morisco C, Sadoshima J, Iaccarino G, Sorriento D. Gambardella J, et al. Among authors: santulli g. Cell Mol Life Sci. 2023 Oct 11;80(11):323. doi: 10.1007/s00018-023-04922-5. Cell Mol Life Sci. 2023. PMID: 37819449 Free PMC article.
Imaging atrial arrhythmic intracellular calcium in intact heart.
Xie W, Santulli G, Guo X, Gao M, Chen BX, Marks AR. Xie W, et al. Among authors: santulli g. J Mol Cell Cardiol. 2013 Nov;64:120-3. doi: 10.1016/j.yjmcc.2013.09.003. Epub 2013 Sep 13. J Mol Cell Cardiol. 2013. PMID: 24041536 Free PMC article.
Calcium release channel RyR2 regulates insulin release and glucose homeostasis.
Santulli G, Pagano G, Sardu C, Xie W, Reiken S, D'Ascia SL, Cannone M, Marziliano N, Trimarco B, Guise TA, Lacampagne A, Marks AR. Santulli G, et al. J Clin Invest. 2015 May;125(5):1968-78. doi: 10.1172/JCI79273. Epub 2015 Apr 6. J Clin Invest. 2015. PMID: 25844899 Free PMC article.
Mitochondrial oxidative stress promotes atrial fibrillation.
Xie W, Santulli G, Reiken SR, Yuan Q, Osborne BW, Chen BX, Marks AR. Xie W, et al. Among authors: santulli g. Sci Rep. 2015 Jul 14;5:11427. doi: 10.1038/srep11427. Sci Rep. 2015. PMID: 26169582 Free PMC article.
276 results