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Molecular correlates of sensitivity to PARP inhibition beyond homologous recombination deficiency in pre-clinical models of colorectal cancer point to wild-type TP53 activity.
Smeby J, Kryeziu K, Berg KCG, Eilertsen IA, Eide PW, Johannessen B, Guren MG, Nesbakken A, Bruun J, Lothe RA, Sveen A. Smeby J, et al. Among authors: nesbakken a. EBioMedicine. 2020 Sep;59:102923. doi: 10.1016/j.ebiom.2020.102923. Epub 2020 Aug 13. EBioMedicine. 2020. PMID: 32799124 Free PMC article.
DNA sequence profiles of the colorectal cancer critical gene set KRAS-BRAF-PIK3CA-PTEN-TP53 related to age at disease onset.
Berg M, Danielsen SA, Ahlquist T, Merok MA, Ågesen TH, Vatn MH, Mala T, Sjo OH, Bakka A, Moberg I, Fetveit T, Mathisen Ø, Husby A, Sandvik O, Nesbakken A, Thiis-Evensen E, Lothe RA. Berg M, et al. Among authors: nesbakken a. PLoS One. 2010 Nov 12;5(11):e13978. doi: 10.1371/journal.pone.0013978. PLoS One. 2010. PMID: 21103049 Free PMC article.
CLC and IFNAR1 are differentially expressed and a global immunity score is distinct between early- and late-onset colorectal cancer.
Ågesen TH, Berg M, Clancy T, Thiis-Evensen E, Cekaite L, Lind GE, Nesland JM, Bakka A, Mala T, Hauss HJ, Fetveit T, Vatn MH, Hovig E, Nesbakken A, Lothe RA, Skotheim RI. Ågesen TH, et al. Among authors: nesbakken a. Genes Immun. 2011 Dec;12(8):653-62. doi: 10.1038/gene.2011.43. Epub 2011 Jun 30. Genes Immun. 2011. PMID: 21716316
144 results