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Dissecting the genetic overlap of smoking behaviors, lung cancer, and chronic obstructive pulmonary disease: A focus on nicotinic receptors and nicotine metabolizing enzyme.
Bray MJ, Chen LS, Fox L, Hancock DB, Culverhouse RC, Hartz SM, Johnson EO, Liu M, McKay JD, Saccone NL, Hokanson JE, Vrieze SI, Tyndale RF, Baker TB, Bierut LJ. Bray MJ, et al. Among authors: culverhouse rc. Genet Epidemiol. 2020 Oct;44(7):748-758. doi: 10.1002/gepi.22331. Epub 2020 Aug 16. Genet Epidemiol. 2020. PMID: 32803792 Free PMC article.
Genetic studies of alcoholism and substance dependence.
Reich T, Hinrichs A, Culverhouse R, Bierut L. Reich T, et al. Am J Hum Genet. 1999 Sep;65(3):599-605. doi: 10.1086/302561. Am J Hum Genet. 1999. PMID: 10441565 Free PMC article. Review. No abstract available.
Covariates in linkage analysis.
Rice JP, Rochberg N, Neuman RJ, Saccone NL, Liu KY, Zhang X, Culverhouse R. Rice JP, et al. Genet Epidemiol. 1999;17 Suppl 1:S691-5. doi: 10.1002/gepi.13701707113. Genet Epidemiol. 1999. PMID: 10597515
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM; COGEND collaborators and GELCC collaborators. Wang JC, et al. Hum Mol Genet. 2009 Aug 15;18(16):3125-35. doi: 10.1093/hmg/ddp231. Epub 2009 May 14. Hum Mol Genet. 2009. PMID: 19443489 Free PMC article.
The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans.
Saccone NL, Wang JC, Breslau N, Johnson EO, Hatsukami D, Saccone SF, Grucza RA, Sun L, Duan W, Budde J, Culverhouse RC, Fox L, Hinrichs AL, Steinbach JH, Wu M, Rice JP, Goate AM, Bierut LJ. Saccone NL, et al. Among authors: culverhouse rc. Cancer Res. 2009 Sep 1;69(17):6848-56. doi: 10.1158/0008-5472.CAN-09-0786. Epub 2009 Aug 25. Cancer Res. 2009. PMID: 19706762 Free PMC article.
The challenge of detecting epistasis (G x G interactions): Genetic Analysis Workshop 16.
An P, Mukherjee O, Chanda P, Yao L, Engelman CD, Huang CH, Zheng T, Kovac IP, Dubé MP, Liang X, Li J, de Andrade M, Culverhouse R, Malzahn D, Manning AK, Clarke GM, Jung J, Province MA. An P, et al. Genet Epidemiol. 2009;33 Suppl 1(0 1):S58-67. doi: 10.1002/gepi.20474. Genet Epidemiol. 2009. PMID: 19924703 Free PMC article.
A genome-wide association study of alcohol dependence.
Bierut LJ, Agrawal A, Bucholz KK, Doheny KF, Laurie C, Pugh E, Fisher S, Fox L, Howells W, Bertelsen S, Hinrichs AL, Almasy L, Breslau N, Culverhouse RC, Dick DM, Edenberg HJ, Foroud T, Grucza RA, Hatsukami D, Hesselbrock V, Johnson EO, Kramer J, Krueger RF, Kuperman S, Lynskey M, Mann K, Neuman RJ, Nöthen MM, Nurnberger JI Jr, Porjesz B, Ridinger M, Saccone NL, Saccone SF, Schuckit MA, Tischfield JA, Wang JC, Rietschel M, Goate AM, Rice JP; Gene, Environment Association Studies Consortium. Bierut LJ, et al. Among authors: culverhouse rc. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5082-7. doi: 10.1073/pnas.0911109107. Epub 2010 Mar 2. Proc Natl Acad Sci U S A. 2010. PMID: 20202923 Free PMC article.
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.
Saccone NL, Culverhouse RC, Schwantes-An TH, Cannon DS, Chen X, Cichon S, Giegling I, Han S, Han Y, Keskitalo-Vuokko K, Kong X, Landi MT, Ma JZ, Short SE, Stephens SH, Stevens VL, Sun L, Wang Y, Wenzlaff AS, Aggen SH, Breslau N, Broderick P, Chatterjee N, Chen J, Heath AC, Heliövaara M, Hoft NR, Hunter DJ, Jensen MK, Martin NG, Montgomery GW, Niu T, Payne TJ, Peltonen L, Pergadia ML, Rice JP, Sherva R, Spitz MR, Sun J, Wang JC, Weiss RB, Wheeler W, Witt SH, Yang BZ, Caporaso NE, Ehringer MA, Eisen T, Gapstur SM, Gelernter J, Houlston R, Kaprio J, Kendler KS, Kraft P, Leppert MF, Li MD, Madden PA, Nöthen MM, Pillai S, Rietschel M, Rujescu D, Schwartz A, Amos CI, Bierut LJ. Saccone NL, et al. Among authors: culverhouse rc. PLoS Genet. 2010 Aug 5;6(8):e1001053. doi: 10.1371/journal.pgen.1001053. PLoS Genet. 2010. PMID: 20700436 Free PMC article.
67 results