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Inhibitor of differentiation-3 mediates high fat diet-induced visceral fat expansion.
Cutchins A, Harmon DB, Kirby JL, Doran AC, Oldham SN, Skaflen M, Klibanov AL, Meller N, Keller SR, Garmey J, McNamara CA. Cutchins A, et al. Among authors: mcnamara ca. Arterioscler Thromb Vasc Biol. 2012 Feb;32(2):317-24. doi: 10.1161/ATVBAHA.111.234856. Epub 2011 Nov 10. Arterioscler Thromb Vasc Biol. 2012. PMID: 22075252 Free PMC article.
Importance of thorough tissue and cellular level characterization of targeted drugs in the evaluation of pharmacodynamic effects.
Bauknight DK, Osinski V, Dasa SSK, Nguyen AT, Marshall MA, Hartman J, Harms M, O'Mahony G, Boucher J, Klibanov AL, McNamara CA, Kelly KA. Bauknight DK, et al. Among authors: mcnamara ca. PLoS One. 2019 Nov 14;14(11):e0224917. doi: 10.1371/journal.pone.0224917. eCollection 2019. PLoS One. 2019. PMID: 31725756 Free PMC article.
In vivo liposomal delivery of PPARα/γ dual agonist tesaglitazar in a model of obesity enriches macrophage targeting and limits liver and kidney drug effects.
Osinski V, Bauknight DK, Dasa SSK, Harms MJ, Kroon T, Marshall MA, Garmey JC, Nguyen AT, Hartman J, Upadhye A, Srikakulapu P, Zhou A, O'Mahony G, Klibanov AL, Kelly KA, Boucher J, McNamara CA. Osinski V, et al. Among authors: mcnamara ca. Theranostics. 2020 Jan 1;10(2):585-601. doi: 10.7150/thno.36572. eCollection 2020. Theranostics. 2020. PMID: 31903139 Free PMC article.
PPARγ and PPARα synergize to induce robust browning of white fat in vivo.
Kroon T, Harms M, Maurer S, Bonnet L, Alexandersson I, Lindblom A, Ahnmark A, Nilsson D, Gennemark P, O'Mahony G, Osinski V, McNamara C, Boucher J. Kroon T, et al. Mol Metab. 2020 Jun;36:100964. doi: 10.1016/j.molmet.2020.02.007. Epub 2020 Feb 18. Mol Metab. 2020. PMID: 32248079 Free PMC article.
Pre-operative aerobic exercise on metabolic health and surgical outcomes in patients receiving bariatric surgery: A pilot trial.
Gilbertson NM, Gaitán JM, Osinski V, Rexrode EA, Garmey JC, Mehaffey JH, Hassinger TE, Kranz S, McNamara CA, Weltman A, Hallowell PT, Malin SK. Gilbertson NM, et al. Among authors: mcnamara ca. PLoS One. 2020 Oct 2;15(10):e0239130. doi: 10.1371/journal.pone.0239130. eCollection 2020. PLoS One. 2020. PMID: 33006980 Free PMC article.
Helix-Loop-Helix Factor Id3 (Inhibitor of Differentiation 3): A Novel Regulator of Hyaluronan-Mediated Adipose Tissue Inflammation.
Misiou A, Garmey JC, Hensien JM, Harmon DB, Osinski V, McSkimming C, Marshall MA, Fischer JW, Grandoch M, McNamara CA. Misiou A, et al. Among authors: mcnamara ca. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):796-807. doi: 10.1161/ATVBAHA.120.315588. Epub 2020 Dec 31. Arterioscler Thromb Vasc Biol. 2021. PMID: 33380173 Free PMC article.
Loss of Id3 (Inhibitor of Differentiation 3) Increases the Number of IgM-Producing B-1b Cells in Ischemic Skeletal Muscle Impairing Blood Flow Recovery During Hindlimb Ischemia.
Osinski V, Srikakulapu P, Haider YM, Marshall MA, Ganta VC, Annex BH, McNamara CA. Osinski V, et al. Among authors: mcnamara ca. Arterioscler Thromb Vasc Biol. 2022 Jan;42(1):6-18. doi: 10.1161/ATVBAHA.120.315501. Epub 2021 Nov 23. Arterioscler Thromb Vasc Biol. 2022. PMID: 34809449 Free PMC article.
B-1b Cells Have Unique Functional Traits Compared to B-1a Cells at Homeostasis and in Aged Hyperlipidemic Mice With Atherosclerosis.
Srikakulapu P, Pattarabanjird T, Upadhye A, Bontha SV, Osinski V, Marshall MA, Garmey J, Deroissart J, Prohaska TA, Witztum JL, Binder CJ, Holodick NE, Rothstein TL, McNamara CA. Srikakulapu P, et al. Among authors: mcnamara ca. Front Immunol. 2022 Jul 22;13:909475. doi: 10.3389/fimmu.2022.909475. eCollection 2022. Front Immunol. 2022. PMID: 35935999 Free PMC article.
143 results