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Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains.
Haenig C, Atias N, Taylor AK, Mazza A, Schaefer MH, Russ J, Riechers SP, Jain S, Coughlin M, Fontaine JF, Freibaum BD, Brusendorf L, Zenkner M, Porras P, Stroedicke M, Schnoegl S, Arnsburg K, Boeddrich A, Pigazzini L, Heutink P, Taylor JP, Kirstein J, Andrade-Navarro MA, Sharan R, Wanker EE. Haenig C, et al. Among authors: freibaum bd. Cell Rep. 2020 Aug 18;32(7):108050. doi: 10.1016/j.celrep.2020.108050. Cell Rep. 2020. PMID: 32814053 Free article.
GGGGCC repeat expansion in C9orf72 compromises nucleocytoplasmic transport.
Freibaum BD, Lu Y, Lopez-Gonzalez R, Kim NC, Almeida S, Lee KH, Badders N, Valentine M, Miller BL, Wong PC, Petrucelli L, Kim HJ, Gao FB, Taylor JP. Freibaum BD, et al. Nature. 2015 Sep 3;525(7567):129-33. doi: 10.1038/nature14974. Epub 2015 Aug 26. Nature. 2015. PMID: 26308899 Free PMC article.
C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles.
Lee KH, Zhang P, Kim HJ, Mitrea DM, Sarkar M, Freibaum BD, Cika J, Coughlin M, Messing J, Molliex A, Maxwell BA, Kim NC, Temirov J, Moore J, Kolaitis RM, Shaw TI, Bai B, Peng J, Kriwacki RW, Taylor JP. Lee KH, et al. Among authors: freibaum bd. Cell. 2016 Oct 20;167(3):774-788.e17. doi: 10.1016/j.cell.2016.10.002. Cell. 2016. PMID: 27768896 Free PMC article.
The Role of Dipeptide Repeats in C9ORF72-Related ALS-FTD.
Freibaum BD, Taylor JP. Freibaum BD, et al. Front Mol Neurosci. 2017 Feb 13;10:35. doi: 10.3389/fnmol.2017.00035. eCollection 2017. Front Mol Neurosci. 2017. PMID: 28243191 Free PMC article. Review.
Identification of small molecule inhibitors of G3BP-driven stress granule formation.
Freibaum BD, Messing J, Nakamura H, Yurtsever U, Wu J, Kim HJ, Hixon J, Lemieux RM, Duffner J, Huynh W, Wong K, White M, Lee C, Meyers RE, Parker R, Taylor JP. Freibaum BD, et al. J Cell Biol. 2024 Mar 4;223(3):e202308083. doi: 10.1083/jcb.202308083. Epub 2024 Jan 29. J Cell Biol. 2024. PMID: 38284934 Free article.
26 results