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Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.
Perez M, Bak DW, Bergholtz SE, Crooks DR, Arimilli BS, Yang Y, Weerapana E, Linehan WM, Meier JL. Perez M, et al. Among authors: linehan wm. J Biol Chem. 2020 Sep 25;295(39):13410-13418. doi: 10.1074/jbc.AC120.014993. Epub 2020 Aug 19. J Biol Chem. 2020. PMID: 32820045 Free PMC article.
Inhibition of tumor cell motility by the interferon-inducible GTPase MxA.
Mushinski JF, Nguyen P, Stevens LM, Khanna C, Lee S, Chung EJ, Lee MJ, Kim YS, Linehan WM, Horisberger MA, Trepel JB. Mushinski JF, et al. Among authors: linehan wm. J Biol Chem. 2009 May 29;284(22):15206-14. doi: 10.1074/jbc.M806324200. Epub 2009 Mar 18. J Biol Chem. 2009. PMID: 19297326 Free PMC article.
Fumarate hydratase deficiency in renal cancer induces glycolytic addiction and hypoxia-inducible transcription factor 1alpha stabilization by glucose-dependent generation of reactive oxygen species.
Sudarshan S, Sourbier C, Kong HS, Block K, Valera Romero VA, Yang Y, Galindo C, Mollapour M, Scroggins B, Goode N, Lee MJ, Gourlay CW, Trepel J, Linehan WM, Neckers L. Sudarshan S, et al. Among authors: linehan wm. Mol Cell Biol. 2009 Aug;29(15):4080-90. doi: 10.1128/MCB.00483-09. Epub 2009 May 26. Mol Cell Biol. 2009. PMID: 19470762 Free PMC article.
UOK 262 cell line, fumarate hydratase deficient (FH-/FH-) hereditary leiomyomatosis renal cell carcinoma: in vitro and in vivo model of an aberrant energy metabolic pathway in human cancer.
Yang Y, Valera VA, Padilla-Nash HM, Sourbier C, Vocke CD, Vira MA, Abu-Asab MS, Bratslavsky G, Tsokos M, Merino MJ, Pinto PA, Srinivasan R, Ried T, Neckers L, Linehan WM. Yang Y, et al. Among authors: linehan wm. Cancer Genet Cytogenet. 2010 Jan 1;196(1):45-55. doi: 10.1016/j.cancergencyto.2009.08.018. Cancer Genet Cytogenet. 2010. PMID: 19963135 Free PMC article.
799 results