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Heterogeneous adaptation of cysteine reactivity to a covalent oncometabolite.
Perez M, Bak DW, Bergholtz SE, Crooks DR, Arimilli BS, Yang Y, Weerapana E, Linehan WM, Meier JL. Perez M, et al. Among authors: meier jl. J Biol Chem. 2020 Sep 25;295(39):13410-13418. doi: 10.1074/jbc.AC120.014993. Epub 2020 Aug 19. J Biol Chem. 2020. PMID: 32820045 Free PMC article.
Co-opting a Bioorthogonal Reaction for Oncometabolite Detection.
Zengeya TT, Garlick JM, Kulkarni RA, Miley M, Roberts AM, Yang Y, Crooks DR, Sourbier C, Linehan WM, Meier JL. Zengeya TT, et al. Among authors: meier jl. J Am Chem Soc. 2016 Dec 14;138(49):15813-15816. doi: 10.1021/jacs.6b09706. Epub 2016 Nov 30. J Am Chem Soc. 2016. PMID: 27960310 Free PMC article.
Impact of a High-fat Diet on Tissue Acyl-CoA and Histone Acetylation Levels.
Carrer A, Parris JLD, Trefely S, Henry RA, Montgomery DC, Torres A, Viola JM, Kuo YM, Blair IA, Meier JL, Andrews AJ, Snyder NW, Wellen KE. Carrer A, et al. Among authors: meier jl. J Biol Chem. 2017 Feb 24;292(8):3312-3322. doi: 10.1074/jbc.M116.750620. Epub 2017 Jan 11. J Biol Chem. 2017. PMID: 28077572 Free PMC article.
Discovering Targets of Non-enzymatic Acylation by Thioester Reactivity Profiling.
Kulkarni RA, Worth AJ, Zengeya TT, Shrimp JH, Garlick JM, Roberts AM, Montgomery DC, Sourbier C, Gibbs BK, Mesaros C, Tsai YC, Das S, Chan KC, Zhou M, Andresson T, Weissman AM, Linehan WM, Blair IA, Snyder NW, Meier JL. Kulkarni RA, et al. Among authors: meier jl. Cell Chem Biol. 2017 Feb 16;24(2):231-242. doi: 10.1016/j.chembiol.2017.01.002. Epub 2017 Feb 2. Cell Chem Biol. 2017. PMID: 28163016 Free PMC article.
Photoinducible Oncometabolite Detection.
Kulkarni RA, Briney CA, Crooks DR, Bergholtz SE, Mushti C, Lockett SJ, Lane AN, Fan TW, Swenson RE, Marston Linehan W, Meier JL. Kulkarni RA, et al. Among authors: meier jl. Chembiochem. 2019 Feb 1;20(3):360-365. doi: 10.1002/cbic.201800651. Epub 2018 Dec 13. Chembiochem. 2019. PMID: 30358041 Free PMC article.
A chemoproteomic portrait of the oncometabolite fumarate.
Kulkarni RA, Bak DW, Wei D, Bergholtz SE, Briney CA, Shrimp JH, Alpsoy A, Thorpe AL, Bavari AE, Crooks DR, Levy M, Florens L, Washburn MP, Frizzell N, Dykhuizen EC, Weerapana E, Linehan WM, Meier JL. Kulkarni RA, et al. Among authors: meier jl. Nat Chem Biol. 2019 Apr;15(4):391-400. doi: 10.1038/s41589-018-0217-y. Epub 2019 Feb 4. Nat Chem Biol. 2019. PMID: 30718813 Free PMC article.
Bioorthogonal oncometabolite ligation.
Briney CA, Najera S, Meier JL. Briney CA, et al. Among authors: meier jl. Methods Enzymol. 2019;622:431-448. doi: 10.1016/bs.mie.2019.02.037. Epub 2019 Mar 14. Methods Enzymol. 2019. PMID: 31155064 Free PMC article.
A Systems Chemoproteomic Analysis of Acyl-CoA/Protein Interaction Networks.
Levy MJ, Montgomery DC, Sardiu ME, Montano JL, Bergholtz SE, Nance KD, Thorpe AL, Fox SD, Lin Q, Andresson T, Florens L, Washburn MP, Meier JL. Levy MJ, et al. Among authors: meier jl. Cell Chem Biol. 2020 Mar 19;27(3):322-333.e5. doi: 10.1016/j.chembiol.2019.11.011. Epub 2019 Dec 10. Cell Chem Biol. 2020. PMID: 31836350 Free PMC article.
Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase-deficient renal cancer.
Crooks DR, Maio N, Lang M, Ricketts CJ, Vocke CD, Gurram S, Turan S, Kim YY, Cawthon GM, Sohelian F, De Val N, Pfeiffer RM, Jailwala P, Tandon M, Tran B, Fan TW, Lane AN, Ried T, Wangsa D, Malayeri AA, Merino MJ, Yang Y, Meier JL, Ball MW, Rouault TA, Srinivasan R, Linehan WM. Crooks DR, et al. Among authors: meier jl. Sci Signal. 2021 Jan 5;14(664):eabc4436. doi: 10.1126/scisignal.abc4436. Sci Signal. 2021. PMID: 33402335 Free PMC article.
184 results