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Wnt/β-catenin Signaling in Tissue Self-Organization.
Pond KW, Doubrovinski K, Thorne CA. Pond KW, et al. Among authors: thorne ca. Genes (Basel). 2020 Aug 14;11(8):939. doi: 10.3390/genes11080939. Genes (Basel). 2020. PMID: 32823838 Free PMC article. Review.
Feedback in the β-catenin destruction complex imparts bistability and cellular memory.
Cantoria MJ, Alizadeh E, Ravi J, Varghese RP, Bunnag N, Pond KW, Kettenbach AN, Ahmed Y, Paek AL, Tyson JJ, Doubrovinski K, Lee E, Thorne CA. Cantoria MJ, et al. Among authors: thorne ca. Proc Natl Acad Sci U S A. 2023 Jan 10;120(2):e2208787120. doi: 10.1073/pnas.2208787120. Epub 2023 Jan 4. Proc Natl Acad Sci U S A. 2023. PMID: 36598937 Free PMC article.
USP47 deubiquitylates Groucho/TLE to promote Wnt-β-catenin signaling.
Kassel S, Hanson AJ, Benchabane H, Saito-Diaz K, Cabel CR, Goldsmith L, Taha M, Kanuganti A, Ng VH, Xu G, Ye F, Picker J, Port F, Boutros M, Weiss VL, Robbins DJ, Thorne CA, Ahmed Y, Lee E. Kassel S, et al. Among authors: thorne ca. Sci Signal. 2023 Feb 7;16(771):eabn8372. doi: 10.1126/scisignal.abn8372. Epub 2023 Feb 7. Sci Signal. 2023. PMID: 36749823 Free PMC article.
The way Wnt works: components and mechanism.
Saito-Diaz K, Chen TW, Wang X, Thorne CA, Wallace HA, Page-McCaw A, Lee E. Saito-Diaz K, et al. Among authors: thorne ca. Growth Factors. 2013 Feb;31(1):1-31. doi: 10.3109/08977194.2012.752737. Epub 2012 Dec 21. Growth Factors. 2013. PMID: 23256519 Free PMC article. Review.
Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors.
Li B, Orton D, Neitzel LR, Astudillo L, Shen C, Long J, Chen X, Kirkbride KC, Doundoulakis T, Guerra ML, Zaias J, Fei DL, Rodriguez-Blanco J, Thorne C, Wang Z, Jin K, Nguyen DM, Sands LR, Marchetti F, Abreu MT, Cobb MH, Capobianco AJ, Lee E, Robbins DJ. Li B, et al. Sci Signal. 2017 Jun 27;10(485):eaak9916. doi: 10.1126/scisignal.aak9916. Sci Signal. 2017. PMID: 28655862 Free PMC article.
43 results