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Cell identity and nucleo-mitochondrial genetic context modulate OXPHOS performance and determine somatic heteroplasmy dynamics.
Lechuga-Vieco AV, Latorre-Pellicer A, Johnston IG, Prota G, Gileadi U, Justo-Méndez R, Acín-Pérez R, Martínez-de-Mena R, Fernández-Toro JM, Jimenez-Blasco D, Mora A, Nicolás-Ávila JA, Santiago DJ, Priori SG, Bolaños JP, Sabio G, Criado LM, Ruíz-Cabello J, Cerundolo V, Jones NS, Enríquez JA. Lechuga-Vieco AV, et al. Among authors: bolanos jp. Sci Adv. 2020 Jul 29;6(31):eaba5345. doi: 10.1126/sciadv.aba5345. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832682 Free PMC article.
Neuronal p38α mediates age-associated neural stem cell exhaustion and cognitive decline.
Moreno-Cugnon L, Revuelta M, Arrizabalaga O, Colie S, Moreno-Valladares M, Jimenez-Blasco D, Gil-Bea F, Llarena I, Bolaños JP, Nebreda AR, Matheu A. Moreno-Cugnon L, et al. Among authors: bolanos jp. Aging Cell. 2019 Dec;18(6):e13044. doi: 10.1111/acel.13044. Epub 2019 Sep 27. Aging Cell. 2019. PMID: 31560167 Free PMC article.
Astrocytic mitochondrial ROS modulate brain metabolism and mouse behaviour.
Vicente-Gutierrez C, Bonora N, Bobo-Jimenez V, Jimenez-Blasco D, Lopez-Fabuel I, Fernandez E, Josephine C, Bonvento G, Enriquez JA, Almeida A, Bolaños JP. Vicente-Gutierrez C, et al. Among authors: bolanos jp. Nat Metab. 2019 Feb;1(2):201-211. doi: 10.1038/s42255-018-0031-6. Epub 2019 Feb 4. Nat Metab. 2019. PMID: 32694785
Fgr kinase is required for proinflammatory macrophage activation during diet-induced obesity.
Acín-Pérez R, Iborra S, Martí-Mateos Y, Cook ECL, Conde-Garrosa R, Petcherski A, Muñoz MDM, Martínez de Mena R, Krishnan KC, Jiménez C, Bolaños JP, Laakso M, Lusis AJ, Shirihai OS, Sancho D, Enríquez JA. Acín-Pérez R, et al. Among authors: bolanos jp. Nat Metab. 2020 Sep;2(9):974-988. doi: 10.1038/s42255-020-00273-8. Epub 2020 Sep 17. Nat Metab. 2020. PMID: 32943786 Free PMC article.
p38γ and p38δ regulate postnatal cardiac metabolism through glycogen synthase 1.
Santamans AM, Montalvo-Romeral V, Mora A, Lopez JA, González-Romero F, Jimenez-Blasco D, Rodríguez E, Pintor-Chocano A, Casanueva-Benítez C, Acín-Pérez R, Leiva-Vega L, Duran J, Guinovart JJ, Jiménez-Borreguero J, Enríquez JA, Villlalba-Orero M, Bolaños JP, Aspichueta P, Vázquez J, González-Terán B, Sabio G. Santamans AM, et al. Among authors: bolanos jp. PLoS Biol. 2021 Nov 10;19(11):e3001447. doi: 10.1371/journal.pbio.3001447. eCollection 2021 Nov. PLoS Biol. 2021. PMID: 34758018 Free PMC article.
161 results