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Loss of Bcl-6-Expressing T Follicular Helper Cells and Germinal Centers in COVID-19.
Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Alter G, Li JZ, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu XG, Padera RF Jr, Pillai S; Massachusetts Consortium on Pathogen Readiness Specimen Working Group. Kaneko N, et al. Among authors: liu j, liu h. Cell. 2020 Oct 1;183(1):143-157.e13. doi: 10.1016/j.cell.2020.08.025. Epub 2020 Aug 19. Cell. 2020. PMID: 32877699 Free PMC article.
Cytotoxic CD4+ T lymphocytes may induce endothelial cell apoptosis in systemic sclerosis.
Maehara T, Kaneko N, Perugino CA, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Murphy SJ, Ghebremichael M, Fox D, Payne AS, Lafyatis R, Stone JH, Khanna D, Pillai S. Maehara T, et al. Among authors: liu h. J Clin Invest. 2020 May 1;130(5):2451-2464. doi: 10.1172/JCI131700. J Clin Invest. 2020. PMID: 31990684 Free PMC article. Clinical Trial.
CD4+ and CD8+ cytotoxic T lymphocytes may induce mesenchymal cell apoptosis in IgG4-related disease.
Perugino CA, Kaneko N, Maehara T, Mattoo H, Kers J, Allard-Chamard H, Mahajan VS, Liu H, Della-Torre E, Murphy SJH, Ghebremichael M, Wallace ZS, Bolster MB, Harvey LM, Mylvaganam G, Tuncay Y, Liang L, Montesi SB, Zhang X, Tinju A, Mochizuki K, Munemura R, Sakamoto M, Moriyama M, Nakamura S, Yosef N, Stone JH, Pillai S. Perugino CA, et al. Among authors: liu h. J Allergy Clin Immunol. 2021 Jan;147(1):368-382. doi: 10.1016/j.jaci.2020.05.022. Epub 2020 May 30. J Allergy Clin Immunol. 2021. PMID: 32485263 Free PMC article.
Reply.
Perugino CA, Liu H, Pillai S. Perugino CA, et al. Among authors: liu h. Arthritis Rheumatol. 2020 Sep;72(9):1585-1586. doi: 10.1002/art.41389. Epub 2020 Jul 20. Arthritis Rheumatol. 2020. PMID: 32524774 No abstract available.
The Loss of Bcl-6 Expressing T Follicular Helper Cells and the Absence of Germinal Centers in COVID-19.
Kaneko N, Kuo HH, Boucau J, Farmer JR, Allard-Chamard H, Mahajan VS, Piechocka-Trocha A, Lefteri K, Osborn M, Bals J, Bartsch YC, Bonheur N, Caradonna TM, Chevalier J, Chowdhury F, Diefenbach TJ, Einkauf K, Fallon J, Feldman J, Finn KK, Garcia-Broncano P, Hartana CA, Hauser BM, Jiang C, Kaplonek P, Karpell M, Koscher EC, Lian X, Liu H, Liu J, Ly NL, Michell AR, Rassadkina Y, Seiger K, Sessa L, Shin S, Singh N, Sun W, Sun X, Ticheli HJ, Waring MT, Zhu AL, Li J, Lingwood D, Schmidt AG, Lichterfeld M, Walker BD, Yu X, Padera RF Jr, Pillai S; Massachusetts Consortium on Pathogen Readiness Specimen Working Group. Kaneko N, et al. Among authors: liu j, liu h. SSRN [Preprint]. 2020 Jul 16:3652322. doi: 10.2139/ssrn.3652322. SSRN. 2020. PMID: 32742244 Free PMC article. Updated. Preprint.
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.
Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team; Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Shrock E, et al. Science. 2020 Nov 27;370(6520):eabd4250. doi: 10.1126/science.abd4250. Epub 2020 Sep 29. Science. 2020. PMID: 32994364 Free PMC article.
SARS-CoV-2 viral load is associated with increased disease severity and mortality.
Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ; Massachusetts Consortium for Pathogen Readiness. Fajnzylber J, et al. Nat Commun. 2020 Oct 30;11(1):5493. doi: 10.1038/s41467-020-19057-5. Nat Commun. 2020. PMID: 33127906 Free PMC article.
Expansion of Cytotoxic CD4+ T cells in the lungs in severe COVID-19.
Kaneko N, Boucau J, Kuo HH, Perugino C, Mahajan VS, Farmer JR, Liu H, Diefenbach TJ, Piechocka-Trocha A, Lefteri K, Waring MT, Premo KR, Walker BD, Li JZ, Gaiha G, Yu XG, Lichterfeld M, Padera RF, Pillai S. Kaneko N, et al. Among authors: liu h. medRxiv [Preprint]. 2021 Mar 26:2021.03.23.21253885. doi: 10.1101/2021.03.23.21253885. medRxiv. 2021. PMID: 33791730 Free PMC article. Updated. Preprint.
Viral Load Kinetics of Severe Acute Respiratory Syndrome Coronavirus 2 in Hospitalized Individuals With Coronavirus Disease 2019.
Regan J, Flynn JP, Rosenthal A, Jordan H, Li Y, Chishti R, Giguel F, Corry H, Coxen K, Fajnzylber J, Gillespie E, Kuritzkes DR, Hacohen N, Goldberg MB, Filbin MR, Yu XG, Baden L, Ribeiro RM, Perelson AS, Conway JM, Li JZ; MGH COVID-19 Collection & Processing Teams. Regan J, et al. Open Forum Infect Dis. 2021 Apr 17;8(8):ofab153. doi: 10.1093/ofid/ofab153. eCollection 2021 Aug. Open Forum Infect Dis. 2021. PMID: 34430669 Free PMC article.
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