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C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Hum Mol Genet. 2021 Apr 26;30(3-4):318-320. doi: 10.1093/hmg/ddaa181.
Hum Mol Genet. 2021.
PMID: 32888026
Free PMC article.
No abstract available.
C9orf72 poly GA RAN-translated protein plays a key role in amyotrophic lateral sclerosis via aggregation and toxicity.
Lee YB, Baskaran P, Gomez-Deza J, Chen HJ, Nishimura AL, Smith BN, Troakes C, Adachi Y, Stepto A, Petrucelli L, Gallo JM, Hirth F, Rogelj B, Guthrie S, Shaw CE.
Lee YB, et al. Among authors: gomez deza j.
Hum Mol Genet. 2017 Dec 15;26(24):4765-4777. doi: 10.1093/hmg/ddx350.
Hum Mol Genet. 2017.
PMID: 28973350
Free PMC article.
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Dipeptide repeat protein inclusions are rare in the spinal cord and almost absent from motor neurons in C9ORF72 mutant amyotrophic lateral sclerosis and are unlikely to cause their degeneration.
Gomez-Deza J, Lee YB, Troakes C, Nolan M, Al-Sarraj S, Gallo JM, Shaw CE.
Gomez-Deza J, et al.
Acta Neuropathol Commun. 2015 Jun 25;3:38. doi: 10.1186/s40478-015-0218-y.
Acta Neuropathol Commun. 2015.
PMID: 26108573
Free PMC article.
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Hexanucleotide repeats in ALS/FTD form length-dependent RNA foci, sequester RNA binding proteins, and are neurotoxic.
Lee YB, Chen HJ, Peres JN, Gomez-Deza J, Attig J, Stalekar M, Troakes C, Nishimura AL, Scotter EL, Vance C, Adachi Y, Sardone V, Miller JW, Smith BN, Gallo JM, Ule J, Hirth F, Rogelj B, Houart C, Shaw CE.
Lee YB, et al. Among authors: gomez deza j.
Cell Rep. 2013 Dec 12;5(5):1178-86. doi: 10.1016/j.celrep.2013.10.049. Epub 2013 Nov 27.
Cell Rep. 2013.
PMID: 24290757
Free PMC article.
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Local production of reactive oxygen species drives vincristine-induced axon degeneration.
Gomez-Deza J, Slavutsky AL, Nebiyou M, Le Pichon CE.
Gomez-Deza J, et al.
Cell Death Dis. 2023 Dec 8;14(12):807. doi: 10.1038/s41419-023-06227-8.
Cell Death Dis. 2023.
PMID: 38065950
Free PMC article.
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