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NCLX is an essential component of mitochondrial Na+/Ca2+ exchange.
Palty R, Silverman WF, Hershfinkel M, Caporale T, Sensi SL, Parnis J, Nolte C, Fishman D, Shoshan-Barmatz V, Herrmann S, Khananshvili D, Sekler I. Palty R, et al. Among authors: sekler i. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):436-41. doi: 10.1073/pnas.0908099107. Epub 2009 Dec 15. Proc Natl Acad Sci U S A. 2010. PMID: 20018762 Free PMC article.
The mitochondrial Na(+)/Ca(2+) exchanger.
Palty R, Sekler I. Palty R, et al. Among authors: sekler i. Cell Calcium. 2012 Jul;52(1):9-15. doi: 10.1016/j.ceca.2012.02.010. Epub 2012 Mar 18. Cell Calcium. 2012. PMID: 22430014 Review.
Pancreatic β-cell Na+ channels control global Ca2+ signaling and oxidative metabolism by inducing Na+ and Ca2+ responses that are propagated into mitochondria.
Nita II, Hershfinkel M, Kantor C, Rutter GA, Lewis EC, Sekler I. Nita II, et al. Among authors: sekler i. FASEB J. 2014 Aug;28(8):3301-12. doi: 10.1096/fj.13-248161. Epub 2014 Apr 9. FASEB J. 2014. PMID: 24719357 Free PMC article.
Our results show that communication of the Na(+) channels with mitochondria shape both global Ca(2+) and metabolism signals linked to insulin secretion in beta cells.- Nita, I. I., Hershfinkel, M., Kantor, C., Rutter, G. A., Lewis, E. C., Sekler, I. .. …
Our results show that communication of the Na(+) channels with mitochondria shape both global Ca(2+) and metabolism signals linked to insuli …
110 results