Xin P - Search Results

1

Dichotomous role of the human mitochondrial Na⁺/Ca2⁺/Li⁺ exchanger NCLX in colorectal cancer growth and metastasis.

Pathak T, Gueguinou M, Walter V, Delierneux C, Johnson MT, Zhang X, Xin P, Yoast RE, Emrich SM, Yochum GS, Sekler I, Koltun WA, Gill DL, Hempel N, Trebak M. Pathak T, et al. Among authors: xin p. Elife. 2020 Sep 11;9:e59686. doi: 10.7554/eLife.59686. Elife. 2020. PMID: 32914752 Free PMC article.

2

The airway smooth muscle sodium/calcium exchanger NCLX is critical for airway remodeling and hyperresponsiveness in asthma.

Johnson MT, Benson JC, Pathak T, Xin P, McKernan AS, Emrich SM, Yoast RE, Walter V, Straub AC, Trebak M. Johnson MT, et al. Among authors: xin p. J Biol Chem. 2022 Aug;298(8):102259. doi: 10.1016/j.jbc.2022.102259. Epub 2022 Jul 14. J Biol Chem. 2022. PMID: 35841929 Free PMC article.

3

Cross-talk between N-terminal and C-terminal domains in stromal interaction molecule 2 (STIM2) determines enhanced STIM2 sensitivity.

Emrich SM, Yoast RE, Xin P, Zhang X, Pathak T, Nwokonko R, Gueguinou MF, Subedi KP, Zhou Y, Ambudkar IS, Hempel N, Machaca K, Gill DL, Trebak M. Emrich SM, et al. Among authors: xin p. J Biol Chem. 2019 Apr 19;294(16):6318-6332. doi: 10.1074/jbc.RA118.006801. Epub 2019 Mar 1. J Biol Chem. 2019. PMID: 30824535 Free PMC article.

4

A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction.

Zhang X, Pathak T, Yoast R, Emrich S, Xin P, Nwokonko RM, Johnson M, Wu S, Delierneux C, Gueguinou M, Hempel N, Putney JW Jr, Gill DL, Trebak M. Zhang X, et al. Among authors: xin p. Nat Commun. 2019 Apr 29;10(1):1971. doi: 10.1038/s41467-019-09593-0. Nat Commun. 2019. PMID: 31036819 Free PMC article.

5

The native ORAI channel trio underlies the diversity of Ca²⁺ signaling events.

Yoast RE, Emrich SM, Zhang X, Xin P, Johnson MT, Fike AJ, Walter V, Hempel N, Yule DI, Sneyd J, Gill DL, Trebak M. Yoast RE, et al. Among authors: xin p. Nat Commun. 2020 May 15;11(1):2444. doi: 10.1038/s41467-020-16232-6. Nat Commun. 2020. PMID: 32415068 Free PMC article.

6

L-type Ca²⁺ channel blockers promote vascular remodeling through activation of STIM proteins.

Johnson MT, Gudlur A, Zhang X, Xin P, Emrich SM, Yoast RE, Courjaret R, Nwokonko RM, Li W, Hempel N, Machaca K, Gill DL, Hogan PG, Trebak M. Johnson MT, et al. Among authors: xin p. Proc Natl Acad Sci U S A. 2020 Jul 21;117(29):17369-17380. doi: 10.1073/pnas.2007598117. Epub 2020 Jul 8. Proc Natl Acad Sci U S A. 2020. PMID: 32641503 Free PMC article.

7

Omnitemporal choreographies of all five STIM/Orai and IP₃Rs underlie the complexity of mammalian Ca²⁺ signaling.

Emrich SM, Yoast RE, Xin P, Arige V, Wagner LE, Hempel N, Gill DL, Sneyd J, Yule DI, Trebak M. Emrich SM, et al. Among authors: xin p. Cell Rep. 2021 Mar 2;34(9):108760. doi: 10.1016/j.celrep.2021.108760. Cell Rep. 2021. PMID: 33657364 Free PMC article.

8

The Mitochondrial Ca²⁺ uniporter is a central regulator of interorganellar Ca²⁺ transfer and NFAT activation.

Yoast RE, Emrich SM, Zhang X, Xin P, Arige V, Pathak T, Benson JC, Johnson MT, Abdelnaby AE, Lakomski N, Hempel N, Han JM, Dupont G, Yule DI, Sneyd J, Trebak M. Yoast RE, et al. Among authors: xin p. J Biol Chem. 2021 Oct;297(4):101174. doi: 10.1016/j.jbc.2021.101174. Epub 2021 Sep 6. J Biol Chem. 2021. PMID: 34499925 Free PMC article.

9

STIM1 is a core trigger of airway smooth muscle remodeling and hyperresponsiveness in asthma.

Johnson MT, Xin P, Benson JC, Pathak T, Walter V, Emrich SM, Yoast RE, Zhang X, Cao G, Panettieri RA Jr, Trebak M. Johnson MT, et al. Among authors: xin p. Proc Natl Acad Sci U S A. 2022 Jan 4;119(1):e2114557118. doi: 10.1073/pnas.2114557118. Proc Natl Acad Sci U S A. 2022. PMID: 34949717 Free PMC article.

10

Distinct pharmacological profiles of ORAI1, ORAI2, and ORAI3 channels.

Zhang X, Xin P, Yoast RE, Emrich SM, Johnson MT, Pathak T, Benson JC, Azimi I, Gill DL, Monteith GR, Trebak M. Zhang X, et al. Among authors: xin p. Cell Calcium. 2020 Nov;91:102281. doi: 10.1016/j.ceca.2020.102281. Epub 2020 Aug 29. Cell Calcium. 2020. PMID: 32896813 Free PMC article.

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