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Rapid disorganization of mechanically interacting systems of mammary acini.
Shi Q, Ghosh RP, Engelke H, Rycroft CH, Cassereau L, Sethian JA, Weaver VM, Liphardt JT. Shi Q, et al. Proc Natl Acad Sci U S A. 2014 Jan 14;111(2):658-63. doi: 10.1073/pnas.1311312110. Epub 2013 Dec 30. Proc Natl Acad Sci U S A. 2014. PMID: 24379367 Free PMC article.
Physical confinement induces malignant transformation in mammary epithelial cells.
Lu YC, Chu T, Hall MS, Fu DJ, Shi Q, Chiu A, An D, Wang LH, Pardo Y, Southard T, Danko CG, Liphardt J, Nikitin AY, Wu M, Fischbach C, Coonrod S, Ma M. Lu YC, et al. Among authors: shi q. Biomaterials. 2019 Oct;217:119307. doi: 10.1016/j.biomaterials.2019.119307. Epub 2019 Jun 26. Biomaterials. 2019. PMID: 31271857 Free PMC article.
Stiff stroma increases breast cancer risk by inducing the oncogene ZNF217.
Northey JJ, Barrett AS, Acerbi I, Hayward MK, Talamantes S, Dean IS, Mouw JK, Ponik SM, Lakins JN, Huang PJ, Wu J, Shi Q, Samson S, Keely PJ, Mukhtar RA, Liphardt JT, Shepherd JA, Hwang ES, Chen YY, Hansen KC, Littlepage LE, Weaver VM. Northey JJ, et al. Among authors: shi q. J Clin Invest. 2020 Nov 2;130(11):5721-5737. doi: 10.1172/JCI129249. J Clin Invest. 2020. PMID: 32721948 Free PMC article. Clinical Trial.
ecDNA hubs drive cooperative intermolecular oncogene expression.
Hung KL, Yost KE, Xie L, Shi Q, Helmsauer K, Luebeck J, Schöpflin R, Lange JT, Chamorro González R, Weiser NE, Chen C, Valieva ME, Wong IT, Wu S, Dehkordi SR, Duffy CV, Kraft K, Tang J, Belk JA, Rose JC, Corces MR, Granja JM, Li R, Rajkumar U, Friedlein J, Bagchi A, Satpathy AT, Tjian R, Mundlos S, Bafna V, Henssen AG, Mischel PS, Liu Z, Chang HY. Hung KL, et al. Among authors: shi q. Nature. 2021 Dec;600(7890):731-736. doi: 10.1038/s41586-021-04116-8. Epub 2021 Nov 24. Nature. 2021. PMID: 34819668 Free PMC article.
The evolutionary dynamics of extrachromosomal DNA in human cancers.
Lange JT, Rose JC, Chen CY, Pichugin Y, Xie L, Tang J, Hung KL, Yost KE, Shi Q, Erb ML, Rajkumar U, Wu S, Taschner-Mandl S, Bernkopf M, Swanton C, Liu Z, Huang W, Chang HY, Bafna V, Henssen AG, Werner B, Mischel PS. Lange JT, et al. Among authors: shi q. Nat Genet. 2022 Oct;54(10):1527-1533. doi: 10.1038/s41588-022-01177-x. Epub 2022 Sep 19. Nat Genet. 2022. PMID: 36123406 Free PMC article.
Bidirectional epigenetic editing reveals hierarchies in gene regulation.
Pacalin NM, Steinhart Z, Shi Q, Belk JA, Dorovskyi D, Kraft K, Parker KR, Shy BR, Marson A, Chang HY. Pacalin NM, et al. Among authors: shi q. Nat Biotechnol. 2024 May 17. doi: 10.1038/s41587-024-02213-3. Online ahead of print. Nat Biotechnol. 2024. PMID: 38760566
Divergent clonal differentiation trajectories of T cell exhaustion.
Daniel B, Yost KE, Hsiung S, Sandor K, Xia Y, Qi Y, Hiam-Galvez KJ, Black M, J Raposo C, Shi Q, Meier SL, Belk JA, Giles JR, Wherry EJ, Chang HY, Egawa T, Satpathy AT. Daniel B, et al. Among authors: shi q. Nat Immunol. 2022 Nov;23(11):1614-1627. doi: 10.1038/s41590-022-01337-5. Epub 2022 Oct 26. Nat Immunol. 2022. PMID: 36289450
7,948 results