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Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology.
Smith RG, Hannon E, De Jager PL, Chibnik L, Lott SJ, Condliffe D, Smith AR, Haroutunian V, Troakes C, Al-Sarraj S, Bennett DA, Powell J, Lovestone S, Schalkwyk L, Mill J, Lunnon K. Smith RG, et al. Among authors: smith ar. Alzheimers Dement. 2018 Dec;14(12):1580-1588. doi: 10.1016/j.jalz.2018.01.017. Epub 2018 Mar 15. Alzheimers Dement. 2018. PMID: 29550519 Free PMC article.
DNA methylation and inflammation marker profiles associated with a history of depression.
Crawford B, Craig Z, Mansell G, White I, Smith A, Spaull S, Imm J, Hannon E, Wood A, Yaghootkar H, Ji Y; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium; Mullins N, Lewis CM, Mill J, Murphy TM. Crawford B, et al. Hum Mol Genet. 2018 Aug 15;27(16):2840-2850. doi: 10.1093/hmg/ddy199. Hum Mol Genet. 2018. PMID: 29790996 Free PMC article.
A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex.
Marzi SJ, Leung SK, Ribarska T, Hannon E, Smith AR, Pishva E, Poschmann J, Moore K, Troakes C, Al-Sarraj S, Beck S, Newman S, Lunnon K, Schalkwyk LC, Mill J. Marzi SJ, et al. Among authors: smith ar. Nat Neurosci. 2018 Nov;21(11):1618-1627. doi: 10.1038/s41593-018-0253-7. Epub 2018 Oct 22. Nat Neurosci. 2018. PMID: 30349106
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.
Lardenoije R, Roubroeks JAY, Pishva E, Leber M, Wagner H, Iatrou A, Smith AR, Smith RG, Eijssen LMT, Kleineidam L, Kawalia A, Hoffmann P, Luck T, Riedel-Heller S, Jessen F, Maier W, Wagner M, Hurlemann R, Kenis G, Ali M, Del Sol A, Mastroeni D, Delvaux E, Coleman PD, Mill J, Rutten BPF, Lunnon K, Ramirez A, van den Hove DLA. Lardenoije R, et al. Among authors: smith ar, smith rg. Clin Epigenetics. 2019 Nov 27;11(1):164. doi: 10.1186/s13148-019-0755-5. Clin Epigenetics. 2019. PMID: 31775875 Free PMC article.
Psychosis-associated DNA methylomic variation in Alzheimer's disease cortex.
Pishva E, Creese B, Smith AR, Viechtbauer W, Proitsi P, van den Hove DLA, Ballard C, Mill J, Lunnon K. Pishva E, et al. Among authors: smith ar. Neurobiol Aging. 2020 May;89:83-88. doi: 10.1016/j.neurobiolaging.2020.01.001. Epub 2020 Jan 8. Neurobiol Aging. 2020. PMID: 32007278
The molecular etiology of Alzheimer's disease.
Smith AR, Mill J, Lunnon K. Smith AR, et al. Brain Pathol. 2020 Sep;30(5):964-965. doi: 10.1111/bpa.12879. Brain Pathol. 2020. PMID: 32654324 Free PMC article.
953 results