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Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.
Broyde J, Simpson DR, Murray D, Paull EO, Chu BW, Tagore S, Jones SJ, Griffin AT, Giorgi FM, Lachmann A, Jackson P, Sweet-Cordero EA, Honig B, Califano A. Broyde J, et al. Among authors: califano a. Nat Biotechnol. 2021 Feb;39(2):215-224. doi: 10.1038/s41587-020-0652-7. Epub 2020 Sep 14. Nat Biotechnol. 2021. PMID: 32929263 Free PMC article.
Reverse engineering cellular networks.
Margolin AA, Wang K, Lim WK, Kustagi M, Nemenman I, Califano A. Margolin AA, et al. Among authors: califano a. Nat Protoc. 2006;1(2):662-71. doi: 10.1038/nprot.2006.106. Nat Protoc. 2006. PMID: 17406294
The transcriptional network for mesenchymal transformation of brain tumours.
Carro MS, Lim WK, Alvarez MJ, Bollo RJ, Zhao X, Snyder EY, Sulman EP, Anne SL, Doetsch F, Colman H, Lasorella A, Aldape K, Califano A, Iavarone A. Carro MS, et al. Among authors: califano a. Nature. 2010 Jan 21;463(7279):318-25. doi: 10.1038/nature08712. Epub 2009 Dec 23. Nature. 2010. PMID: 20032975 Free PMC article.
Towards patient-based cancer therapeutics.
Cancer Target Discovery and Development Network; Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, Sordella R, Stein L, Trotman LC, Califano A, Dalla-Favera R, Ferrando A, Iavarone A, Pasqualucci L, Silva J, Stockwell BR, Hahn WC, Chin L, DePinho RA, Boehm JS, Gopal S, Huang A, Root DE, Weir BA, Gerhard DS, Zenklusen JC, Roth MG, White MA, Minna JD, MacMillan JB, Posner BA. Cancer Target Discovery and Development Network, et al. Among authors: califano a. Nat Biotechnol. 2010 Sep;28(9):904-6. doi: 10.1038/nbt0910-904. Nat Biotechnol. 2010. PMID: 20829823 Free PMC article.
Reverse engineering of TLX oncogenic transcriptional networks identifies RUNX1 as tumor suppressor in T-ALL.
Della Gatta G, Palomero T, Perez-Garcia A, Ambesi-Impiombato A, Bansal M, Carpenter ZW, De Keersmaecker K, Sole X, Xu L, Paietta E, Racevskis J, Wiernik PH, Rowe JM, Meijerink JP, Califano A, Ferrando AA. Della Gatta G, et al. Among authors: califano a. Nat Med. 2012 Feb 26;18(3):436-40. doi: 10.1038/nm.2610. Nat Med. 2012. PMID: 22366949 Free PMC article.
Structure-based prediction of protein-protein interactions on a genome-wide scale.
Zhang QC, Petrey D, Deng L, Qiang L, Shi Y, Thu CA, Bisikirska B, Lefebvre C, Accili D, Hunter T, Maniatis T, Califano A, Honig B. Zhang QC, et al. Among authors: califano a. Nature. 2012 Oct 25;490(7421):556-60. doi: 10.1038/nature11503. Epub 2012 Sep 30. Nature. 2012. PMID: 23023127 Free PMC article.
346 results