Sweet-Cordero EA - Search Results

1

Oncoprotein-specific molecular interaction maps (SigMaps) for cancer network analyses.

Broyde J, Simpson DR, Murray D, Paull EO, Chu BW, Tagore S, Jones SJ, Griffin AT, Giorgi FM, Lachmann A, Jackson P, Sweet-Cordero EA, Honig B, Califano A. Broyde J, et al. Nat Biotechnol. 2021 Feb;39(2):215-224. doi: 10.1038/s41587-020-0652-7. Epub 2020 Sep 14. Nat Biotechnol. 2021. PMID: 32929263 Free PMC article.

2

Two is better than one: combining IGF1R and MEK blockade as a promising novel treatment strategy against KRAS-mutant lung cancer.

Chen R, Sweet-Cordero EA. Chen R, et al. Cancer Discov. 2013 May;3(5):491-3. doi: 10.1158/2159-8290.CD-13-0128. Cancer Discov. 2013. PMID: 23658296 Free PMC article.

3

Molecular definition of a metastatic lung cancer state reveals a targetable CD109-Janus kinase-Stat axis.

Chuang CH, Greenside PG, Rogers ZN, Brady JJ, Yang D, Ma RK, Caswell DR, Chiou SH, Winters AF, Grüner BM, Ramaswami G, Spencley AL, Kopecky KE, Sayles LC, Sweet-Cordero EA, Li JB, Kundaje A, Winslow MM. Chuang CH, et al. Nat Med. 2017 Mar;23(3):291-300. doi: 10.1038/nm.4285. Epub 2017 Feb 13. Nat Med. 2017. PMID: 28191885 Free PMC article.

4

Oncogenic KRAS Regulates Amino Acid Homeostasis and Asparagine Biosynthesis via ATF4 and Alters Sensitivity to L-Asparaginase.

Gwinn DM, Lee AG, Briones-Martin-Del-Campo M, Conn CS, Simpson DR, Scott AI, Le A, Cowan TM, Ruggero D, Sweet-Cordero EA. Gwinn DM, et al. Cancer Cell. 2018 Jan 8;33(1):91-107.e6. doi: 10.1016/j.ccell.2017.12.003. Cancer Cell. 2018. PMID: 29316436 Free PMC article.

5

Antitumor activity of an engineered decoy receptor targeting CLCF1-CNTFR signaling in lung adenocarcinoma.

Kim JW, Marquez CP, Kostyrko K, Koehne AL, Marini K, Simpson DR, Lee AG, Leung SG, Sayles LC, Shrager J, Ferrer I, Paz-Ares L, Gephart MH, Vicent S, Cochran JR, Sweet-Cordero EA. Kim JW, et al. Nat Med. 2019 Nov;25(11):1783-1795. doi: 10.1038/s41591-019-0612-2. Epub 2019 Nov 7. Nat Med. 2019. PMID: 31700175 Free PMC article.

6

Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and Susceptibilities.

Kelly MR, Kostyrko K, Han K, Mooney NA, Jeng EE, Spees K, Dinh PT, Abbott KL, Gwinn DM, Sweet-Cordero EA, Bassik MC, Jackson PK. Kelly MR, et al. Cancer Discov. 2020 Dec;10(12):1950-1967. doi: 10.1158/2159-8290.CD-19-1274. Epub 2020 Jul 29. Cancer Discov. 2020. PMID: 32727735 Free PMC article.

7

An Expanded Tool Kit for Modeling the Oncogenic Functions of KRAS.

Kostyrko K, Sweet-Cordero EA. Kostyrko K, et al. Cancer Discov. 2020 Nov;10(11):1626-1628. doi: 10.1158/2159-8290.CD-20-1221. Cancer Discov. 2020. PMID: 33139339

8

UHRF1 is a mediator of KRAS driven oncogenesis in lung adenocarcinoma.

Kostyrko K, Román M, Lee AG, Simpson DR, Dinh PT, Leung SG, Marini KD, Kelly MR, Broyde J, Califano A, Jackson PK, Sweet-Cordero EA. Kostyrko K, et al. Among authors: sweet cordero ea. Nat Commun. 2023 Jul 5;14(1):3966. doi: 10.1038/s41467-023-39591-2. Nat Commun. 2023. PMID: 37407562 Free PMC article.

9

Wilms tumor 1 (WT1) regulates KRAS-driven oncogenesis and senescence in mouse and human models.

Vicent S, Chen R, Sayles LC, Lin C, Walker RG, Gillespie AK, Subramanian A, Hinkle G, Yang X, Saif S, Root DE, Huff V, Hahn WC, Sweet-Cordero EA. Vicent S, et al. J Clin Invest. 2010 Nov;120(11):3940-52. doi: 10.1172/JCI44165. Epub 2010 Oct 25. J Clin Invest. 2010. PMID: 20972333 Free PMC article.

10

An integrative approach unveils FOSL1 as an oncogene vulnerability in KRAS-driven lung and pancreatic cancer.

Vallejo A, Perurena N, Guruceaga E, Mazur PK, Martinez-Canarias S, Zandueta C, Valencia K, Arricibita A, Gwinn D, Sayles LC, Chuang CH, Guembe L, Bailey P, Chang DK, Biankin A, Ponz-Sarvise M, Andersen JB, Khatri P, Bozec A, Sweet-Cordero EA, Sage J, Lecanda F, Vicent S. Vallejo A, et al. Nat Commun. 2017 Feb 21;8:14294. doi: 10.1038/ncomms14294. Nat Commun. 2017. PMID: 28220783 Free PMC article.

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