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Metaplastic breast cancers frequently express immune checkpoint markers FOXP3 and PD-L1.
Kalaw E, Lim M, Kutasovic JR, Sokolova A, Taege L, Johnstone K, Bennett J, Saunus JM, Niland C, Ferguson K, Gresshoff I, Bettington M, Pathmanathan N, Tse GM, Papadimos D, Pathmanathan R, Harris G, Yamaguchi R, Tan PH, Fox S, O'Toole SA, Simpson PT, Lakhani SR, McCart Reed AE. Kalaw E, et al. Among authors: fox s. Br J Cancer. 2020 Nov;123(11):1665-1672. doi: 10.1038/s41416-020-01065-3. Epub 2020 Sep 17. Br J Cancer. 2020. PMID: 32939056 Free PMC article.
The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy.
Tan EY, Yan M, Campo L, Han C, Takano E, Turley H, Candiloro I, Pezzella F, Gatter KC, Millar EK, O'Toole SA, McNeil CM, Crea P, Segara D, Sutherland RL, Harris AL, Fox SB. Tan EY, et al. Among authors: fox sb. Br J Cancer. 2009 Jan 27;100(2):405-11. doi: 10.1038/sj.bjc.6604844. Br J Cancer. 2009. PMID: 19165203 Free PMC article.
Loss of STARD10 expression identifies a group of poor prognosis breast cancers independent of HER2/Neu and triple negative status.
Murphy NC, Biankin AV, Millar EK, McNeil CM, O'Toole SA, Segara D, Crea P, Olayioye MA, Lee CS, Fox SB, Morey AL, Christie M, Musgrove EA, Daly RJ, Lindeman GJ, Henshall SM, Visvader JE, Sutherland RL. Murphy NC, et al. Int J Cancer. 2010 Mar 15;126(6):1445-53. doi: 10.1002/ijc.24826. Int J Cancer. 2010. PMID: 19676041 Free article.
Subtypes of familial breast tumours revealed by expression and copy number profiling.
Waddell N, Arnold J, Cocciardi S, da Silva L, Marsh A, Riley J, Johnstone CN, Orloff M, Assie G, Eng C, Reid L, Keith P, Yan M, Fox S, Devilee P, Godwin AK, Hogervorst FB, Couch F; kConFab Investigators; Grimmond S, Flanagan JM, Khanna K, Simpson PT, Lakhani SR, Chenevix-Trench G. Waddell N, et al. Among authors: fox s. Breast Cancer Res Treat. 2010 Oct;123(3):661-77. doi: 10.1007/s10549-009-0653-1. Epub 2009 Dec 4. Breast Cancer Res Treat. 2010. PMID: 19960244
HER3 and downstream pathways are involved in colonization of brain metastases from breast cancer.
Da Silva L, Simpson PT, Smart CE, Cocciardi S, Waddell N, Lane A, Morrison BJ, Vargas AC, Healey S, Beesley J, Pakkiri P, Parry S, Kurniawan N, Reid L, Keith P, Faria P, Pereira E, Skalova A, Bilous M, Balleine RL, Do H, Dobrovic A, Fox S, Franco M, Reynolds B, Khanna KK, Cummings M, Chenevix-Trench G, Lakhani SR. Da Silva L, et al. Among authors: fox s. Breast Cancer Res. 2010;12(4):R46. doi: 10.1186/bcr2603. Epub 2010 Jul 6. Breast Cancer Res. 2010. PMID: 20604919 Free PMC article.
2,519 results