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Discovery of broad-spectrum fungicides that block septin-dependent infection processes of pathogenic fungi.
He M, Su J, Xu Y, Chen J, Chern M, Lei M, Qi T, Wang Z, Ryder LS, Tang B, Osés-Ruiz M, Zhu K, Cao Y, Yan X, Eisermann I, Luo Y, Li W, Wang J, Yin J, Lam SM, Peng G, Sun X, Zhu X, Ma B, Wang J, Liu J, Qing H, Song L, Wang L, Hou Q, Qin P, Li Y, Fan J, Li D, Wang Y, Wang X, Jiang L, Shui G, Xia Y, Gong G, Huang F, Wang W, Wu X, Li P, Zhu L, Li S, Talbot NJ, Chen X. He M, et al. Among authors: ryder ls. Nat Microbiol. 2020 Dec;5(12):1565-1575. doi: 10.1038/s41564-020-00790-y. Epub 2020 Sep 21. Nat Microbiol. 2020. PMID: 32958858
Tpc1 is an important Zn(II)2Cys6 transcriptional regulator required for polarized growth and virulence in the rice blast fungus.
Galhano R, Illana A, Ryder LS, Rodríguez-Romero J, Demuez M, Badaruddin M, Martinez-Rocha AL, Soanes DM, Studholme DJ, Talbot NJ, Sesma A. Galhano R, et al. Among authors: ryder ls. PLoS Pathog. 2017 Jul 24;13(7):e1006516. doi: 10.1371/journal.ppat.1006516. eCollection 2017 Jul. PLoS Pathog. 2017. PMID: 28742127 Free PMC article.
26 results