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Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy.
Mastellos DC, Pires da Silva BGP, Fonseca BAL, Fonseca NP, Auxiliadora-Martins M, Mastaglio S, Ruggeri A, Sironi M, Radermacher P, Chrysanthopoulou A, Skendros P, Ritis K, Manfra I, Iacobelli S, Huber-Lang M, Nilsson B, Yancopoulou D, Connolly ES, Garlanda C, Ciceri F, Risitano AM, Calado RT, Lambris JD. Mastellos DC, et al. Among authors: sironi m. Clin Immunol. 2020 Nov;220:108598. doi: 10.1016/j.clim.2020.108598. Epub 2020 Sep 19. Clin Immunol. 2020. PMID: 32961333 Free PMC article.
Pathogen recognition by the long pentraxin PTX3.
Moalli F, Jaillon S, Inforzato A, Sironi M, Bottazzi B, Mantovani A, Garlanda C. Moalli F, et al. Among authors: sironi m. J Biomed Biotechnol. 2011;2011:830421. doi: 10.1155/2011/830421. Epub 2011 Jun 2. J Biomed Biotechnol. 2011. PMID: 21716666 Free PMC article. Review.
Recognition and inhibition of SARS-CoV-2 by humoral innate immunity pattern recognition molecules.
Stravalaci M, Pagani I, Paraboschi EM, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M, Perucchini C, Varani L, Matkovic M, Cavalli A, Cesana D, Gallina P, Pedemonte N, Capurro V, Clementi N, Mancini N, Invernizzi P, Bayarri-Olmos R, Garred P, Rappuoli R, Duga S, Bottazzi B, Uguccioni M, Asselta R, Vicenzi E, Mantovani A, Garlanda C. Stravalaci M, et al. Among authors: sironi m. Nat Immunol. 2022 Feb;23(2):275-286. doi: 10.1038/s41590-021-01114-w. Epub 2022 Jan 31. Nat Immunol. 2022. PMID: 35102342
Macrophage expression and prognostic significance of the long pentraxin PTX3 in COVID-19.
Brunetta E, Folci M, Bottazzi B, De Santis M, Gritti G, Protti A, Mapelli SN, Bonovas S, Piovani D, Leone R, My I, Zanon V, Spata G, Bacci M, Supino D, Carnevale S, Sironi M, Davoudian S, Peano C, Landi F, Di Marco F, Raimondi F, Gianatti A, Angelini C, Rambaldi A, Garlanda C, Ciccarelli M, Cecconi M, Mantovani A. Brunetta E, et al. Among authors: sironi m. Nat Immunol. 2021 Jan;22(1):19-24. doi: 10.1038/s41590-020-00832-x. Epub 2020 Nov 18. Nat Immunol. 2021. PMID: 33208929 Free article.
Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology.
Oggioni M, Mercurio D, Minuta D, Fumagalli S, Popiolek-Barczyk K, Sironi M, Ciechanowska A, Ippati S, De Blasio D, Perego C, Mika J, Garlanda C, De Simoni MG. Oggioni M, et al. Among authors: sironi m. Sci Rep. 2021 May 5;11(1):9616. doi: 10.1038/s41598-021-89032-7. Sci Rep. 2021. PMID: 33953334 Free PMC article.
Reply to: Hultström et al., Genetic determinants of mannose-binding lectin activity predispose to thromboembolic complications in critical COVID-19. Mannose-binding lectin genetics in COVID-19.
Asselta R, Paraboschi EM, Stravalaci M, Invernizzi P, Bonfanti P, Biondi A, Pagani I, Pedotti M, Doni A, Scavello F, Mapelli SN, Sironi M, Perucchini C, Varani L, Matkovic M, Cavalli A, Cesana D, Gallina P, Pedemonte N, Capurro V, Clementi N, Mancini N, Bayarri-Olmos R, Garred P, Rappuoli R, Duga S, Bottazzi B, Uguccioni M, Vicenzi E, Mantovani A, Garlanda C. Asselta R, et al. Among authors: sironi m. Nat Immunol. 2022 Jun;23(6):865-867. doi: 10.1038/s41590-022-01228-9. Epub 2022 May 27. Nat Immunol. 2022. PMID: 35624207 No abstract available.
Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant.
Bottazzi B, Santini L, Savino S, Giuliani MM, Dueñas Díez AI, Mancuso G, Beninati C, Sironi M, Valentino S, Deban L, Garlanda C, Teti G, Pizza M, Rappuoli R, Mantovani A. Bottazzi B, et al. Among authors: sironi m. PLoS One. 2015 Mar 18;10(3):e0120807. doi: 10.1371/journal.pone.0120807. eCollection 2015. PLoS One. 2015. PMID: 25786110 Free PMC article.
Regulation of leukocyte recruitment by the long pentraxin PTX3.
Deban L, Russo RC, Sironi M, Moalli F, Scanziani M, Zambelli V, Cuccovillo I, Bastone A, Gobbi M, Valentino S, Doni A, Garlanda C, Danese S, Salvatori G, Sassano M, Evangelista V, Rossi B, Zenaro E, Constantin G, Laudanna C, Bottazzi B, Mantovani A. Deban L, et al. Among authors: sironi m. Nat Immunol. 2010 Apr;11(4):328-34. doi: 10.1038/ni.1854. Epub 2010 Mar 7. Nat Immunol. 2010. PMID: 20208538 Free article.
500 results