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Polygenic risk score for the prediction of breast cancer is related to lesser terminal duct lobular unit involution of the breast.
Bodelon C, Oh H, Derkach A, Sampson JN, Sprague BL, Vacek P, Weaver DL, Fan S, Palakal M, Papathomas D, Xiang J, Patel DA, Linville L, Clare SE, Visscher DW, Mies C, Hewitt SM, Brinton LA, Storniolo AMV, He C, Chanock SJ, Garcia-Closas M, Gierach GL, Figueroa JD. Bodelon C, et al. Among authors: he c. NPJ Breast Cancer. 2020 Sep 7;6:41. doi: 10.1038/s41523-020-00184-7. eCollection 2020. NPJ Breast Cancer. 2020. PMID: 32964115 Free PMC article.
Reproductive aging-associated common genetic variants and the risk of breast cancer.
He C, Chasman DI, Dreyfus J, Hwang SJ, Ruiter R, Sanna S, Buring JE, Fernández-Rhodes L, Franceschini N, Hankinson SE, Hofman A, Lunetta KL, Palmieri G, Porcu E, Rivadeneira F, Rose LM, Splansky GL, Stolk L, Uitterlinden AG, Chanock SJ, Crisponi L, Demerath EW, Murabito JM, Ridker PM, Stricker BH, Hunter DJ. He C, et al. Breast Cancer Res. 2012 Mar 20;14(2):R54. doi: 10.1186/bcr3155. Breast Cancer Res. 2012. PMID: 22433456 Free PMC article.
Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.
Day FR, Ruth KS, Thompson DJ, Lunetta KL, Pervjakova N, Chasman DI, Stolk L, Finucane HK, Sulem P, Bulik-Sullivan B, Esko T, Johnson AD, Elks CE, Franceschini N, He C, Altmaier E, Brody JA, Franke LL, Huffman JE, Keller MF, McArdle PF, Nutile T, Porcu E, Robino A, Rose LM, Schick UM, Smith JA, Teumer A, Traglia M, Vuckovic D, Yao J, Zhao W, Albrecht E, Amin N, Corre T, Hottenga JJ, Mangino M, Smith AV, Tanaka T, Abecasis G, Andrulis IL, Anton-Culver H, Antoniou AC, Arndt V, Arnold AM, Barbieri C, Beckmann MW, Beeghly-Fadiel A, Benitez J, Bernstein L, Bielinski SJ, Blomqvist C, Boerwinkle E, Bogdanova NV, Bojesen SE, Bolla MK, Borresen-Dale AL, Boutin TS, Brauch H, Brenner H, Brüning T, Burwinkel B, Campbell A, Campbell H, Chanock SJ, Chapman JR, Chen YI, Chenevix-Trench G, Couch FJ, Coviello AD, Cox A, Czene K, Darabi H, De Vivo I, Demerath EW, Dennis J, Devilee P, Dörk T, Dos-Santos-Silva I, Dunning AM, Eicher JD, Fasching PA, Faul JD, Figueroa J, Flesch-Janys D, Gandin I, Garcia ME, García-Closas M, Giles GG, Girotto GG, Goldberg MS, González-Neira A, Goodarzi MO, Grove ML, Gudbjartsson DF, Guénel P, Guo X, Haiman CA, Hall P, Hamann U, Henderson BE, Hocking LJ, Hofman A, … See abstract for full author list ➔ Day FR, et al. Among authors: he c. Nat Genet. 2015 Nov;47(11):1294-1303. doi: 10.1038/ng.3412. Epub 2015 Sep 28. Nat Genet. 2015. PMID: 26414677 Free PMC article.
Ages at menarche- and menopause-related genetic variants in relation to terminal duct lobular unit involution in normal breast tissue.
Oh H, Bodelon C, Palakal M, Chatterjee N, Sherman ME, Linville L, Geller BM, Vacek PM, Weaver DL, Chicoine RE, Papathomas D, Patel DA, Xiang J, Clare SE, Visscher DW, Mies C, Hewitt SM, Brinton LA, Storniolo AM, He C, Garcia-Closas M, Chanock SJ, Gierach GL, Figueroa JD. Oh H, et al. Among authors: he c. Breast Cancer Res Treat. 2016 Jul;158(2):341-50. doi: 10.1007/s10549-016-3859-z. Epub 2016 Jun 24. Breast Cancer Res Treat. 2016. PMID: 27342457 Free PMC article.
Association between breast cancer genetic susceptibility variants and terminal duct lobular unit involution of the breast.
Bodelon C, Oh H, Chatterjee N, Garcia-Closas M, Palakal M, Sherman ME, Pfeiffer RM, Geller B, Vacek P, Weaver DL, Chicoine R, Papathomas D, Xiang J, Patel DA, Khodr ZG, Linville L, Clare SE, Visscher DW, Mies C, Hewitt SM, Brinton LA, Storniolo AMV, He C, Chanock SJ, Gierach GL, Figueroa JD. Bodelon C, et al. Among authors: he c. Int J Cancer. 2017 Feb 15;140(4):825-832. doi: 10.1002/ijc.30512. Epub 2016 Nov 18. Int J Cancer. 2017. PMID: 27859137 Free PMC article.
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