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RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer.
Spit M, Fenderico N, Jordens I, Radaszkiewicz T, Lindeboom RG, Bugter JM, Cristobal A, Ootes L, van Osch M, Janssen E, Boonekamp KE, Hanakova K, Potesil D, Zdrahal Z, Boj SF, Medema JP, Bryja V, Koo BK, Vermeulen M, Maurice MM. Spit M, et al. EMBO J. 2020 Sep 15;39(18):e103932. doi: 10.15252/embj.2019103932. Epub 2020 Aug 10. EMBO J. 2020. PMID: 32965059 Free PMC article.
Axin cancer mutants form nanoaggregates to rewire the Wnt signaling network.
Anvarian Z, Nojima H, van Kappel EC, Madl T, Spit M, Viertler M, Jordens I, Low TY, van Scherpenzeel RC, Kuper I, Richter K, Heck AJ, Boelens R, Vincent JP, Rüdiger SG, Maurice MM. Anvarian Z, et al. Among authors: spit m. Nat Struct Mol Biol. 2016 Apr;23(4):324-32. doi: 10.1038/nsmb.3191. Epub 2016 Mar 14. Nat Struct Mol Biol. 2016. PMID: 26974125
Current perspectives on inhibitory SMAD7 in health and disease.
de Ceuninck van Capelle C, Spit M, Ten Dijke P. de Ceuninck van Capelle C, et al. Among authors: spit m. Crit Rev Biochem Mol Biol. 2020 Dec;55(6):691-715. doi: 10.1080/10409238.2020.1828260. Epub 2020 Oct 20. Crit Rev Biochem Mol Biol. 2020. PMID: 33081543 Review.
Linear ubiquitination at a glance.
Spit M, Rieser E, Walczak H. Spit M, et al. J Cell Sci. 2019 Jan 18;132(2):jcs208512. doi: 10.1242/jcs.208512. J Cell Sci. 2019. PMID: 30659056 Review.
12 results