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Bone Marrow Mesenchymal Stem Cells Support Acute Myeloid Leukemia Bioenergetics and Enhance Antioxidant Defense and Escape from Chemotherapy.
Forte D, García-Fernández M, Sánchez-Aguilera A, Stavropoulou V, Fielding C, Martín-Pérez D, López JA, Costa ASH, Tronci L, Nikitopoulou E, Barber M, Gallipoli P, Marando L, Fernández de Castillejo CL, Tzankov A, Dietmann S, Cavo M, Catani L, Curti A, Vázquez J, Frezza C, Huntly BJ, Schwaller J, Méndez-Ferrer S. Forte D, et al. Among authors: huntly bj. Cell Metab. 2020 Nov 3;32(5):829-843.e9. doi: 10.1016/j.cmet.2020.09.001. Epub 2020 Sep 22. Cell Metab. 2020. PMID: 32966766 Free PMC article.
Targeting cancer stem cells.
Kvinlaug BT, Huntly BJ. Kvinlaug BT, et al. Among authors: huntly bj. Expert Opin Ther Targets. 2007 Jul;11(7):915-27. doi: 10.1517/14728222.11.7.915. Expert Opin Ther Targets. 2007. PMID: 17614760 Review.
Leukemia stem cells in acute myeloid leukemia.
Chan WI, Huntly BJ. Chan WI, et al. Among authors: huntly bj. Semin Oncol. 2008 Aug;35(4):326-35. doi: 10.1053/j.seminoncol.2008.04.003. Semin Oncol. 2008. PMID: 18692683 Review.
Recent advances in acute myeloid leukemia stem cell biology.
Horton SJ, Huntly BJ. Horton SJ, et al. Among authors: huntly bj. Haematologica. 2012 Jul;97(7):966-74. doi: 10.3324/haematol.2011.054734. Epub 2012 Apr 17. Haematologica. 2012. PMID: 22511496 Free PMC article. Review.
The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.
Giotopoulos G, Chan WI, Horton SJ, Ruau D, Gallipoli P, Fowler A, Crawley C, Papaemmanuil E, Campbell PJ, Göttgens B, Van Deursen JM, Cole PA, Huntly BJ. Giotopoulos G, et al. Among authors: huntly bj. Oncogene. 2016 Jan 21;35(3):279-89. doi: 10.1038/onc.2015.92. Epub 2015 Apr 20. Oncogene. 2016. PMID: 25893291 Free PMC article.
A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.
Giotopoulos G, van der Weyden L, Osaki H, Rust AG, Gallipoli P, Meduri E, Horton SJ, Chan WI, Foster D, Prinjha RK, Pimanda JE, Tenen DG, Vassiliou GS, Koschmieder S, Adams DJ, Huntly BJ. Giotopoulos G, et al. Among authors: huntly bj. J Exp Med. 2015 Sep 21;212(10):1551-69. doi: 10.1084/jem.20141661. Epub 2015 Aug 24. J Exp Med. 2015. PMID: 26304963 Free PMC article.
Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition.
Sciacovelli M, Gonçalves E, Johnson TI, Zecchini VR, da Costa AS, Gaude E, Drubbel AV, Theobald SJ, Abbo SR, Tran MG, Rajeeve V, Cardaci S, Foster S, Yun H, Cutillas P, Warren A, Gnanapragasam V, Gottlieb E, Franze K, Huntly B, Maher ER, Maxwell PH, Saez-Rodriguez J, Frezza C. Sciacovelli M, et al. Nature. 2016 Aug 31;537(7621):544-547. doi: 10.1038/nature19353. Nature. 2016. PMID: 27580029 Free PMC article.
146 results