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Comparative genomics guided discovery of two missing archaeal enzyme families involved in the biosynthesis of the pterin moiety of tetrahydromethanopterin and tetrahydrofolate.
de Crécy-Lagard V, Phillips G, Grochowski LL, El Yacoubi B, Jenney F, Adams MW, Murzin AG, White RH. de Crécy-Lagard V, et al. Among authors: murzin ag. ACS Chem Biol. 2012 Nov 16;7(11):1807-16. doi: 10.1021/cb300342u. Epub 2012 Sep 7. ACS Chem Biol. 2012. PMID: 22931285 Free PMC article.
Biochemical and structural studies of conserved Maf proteins revealed nucleotide pyrophosphatases with a preference for modified nucleotides.
Tchigvintsev A, Tchigvintsev D, Flick R, Popovic A, Dong A, Xu X, Brown G, Lu W, Wu H, Cui H, Dombrowski L, Joo JC, Beloglazova N, Min J, Savchenko A, Caudy AA, Rabinowitz JD, Murzin AG, Yakunin AF. Tchigvintsev A, et al. Among authors: murzin ag. Chem Biol. 2013 Nov 21;20(11):1386-98. doi: 10.1016/j.chembiol.2013.09.011. Epub 2013 Oct 24. Chem Biol. 2013. PMID: 24210219 Free PMC article.
Biochemical and structural characterization of a novel family of cystathionine beta-synthase domain proteins fused to a Zn ribbon-like domain.
Proudfoot M, Sanders SA, Singer A, Zhang R, Brown G, Binkowski A, Xu L, Lukin JA, Murzin AG, Joachimiak A, Arrowsmith CH, Edwards AM, Savchenko AV, Yakunin AF. Proudfoot M, et al. Among authors: murzin ag. J Mol Biol. 2008 Jan 4;375(1):301-15. doi: 10.1016/j.jmb.2007.10.060. Epub 2007 Nov 1. J Mol Biol. 2008. PMID: 18021800 Free PMC article.
114 results