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7,099 results

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Clinical usefulness of multigene screening with phenotype-driven bioinformatics analysis for the diagnosis of patients with monogenic diabetes or severe insulin resistance.
Hosoe J, Miya F, Kadowaki H, Fujiwara T, Suzuki K, Kato T, Waki H, Sasako T, Aizu K, Yamamura N, Sasaki F, Kurano M, Hara K, Tanaka M, Ishiura H, Tsuji S, Honda K, Yoshimura J, Morishita S, Matsuzawa F, Aikawa SI, Boroevich KA, Nangaku M, Okada Y, Tsunoda T, Shojima N, Yamauchi T, Kadowaki T. Hosoe J, et al. Among authors: okada y. Diabetes Res Clin Pract. 2020 Nov;169:108461. doi: 10.1016/j.diabres.2020.108461. Epub 2020 Sep 22. Diabetes Res Clin Pract. 2020. PMID: 32971154
Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese.
Myouzen K, Kochi Y, Okada Y, Terao C, Suzuki A, Ikari K, Tsunoda T, Takahashi A, Kubo M, Taniguchi A, Matsuda F, Ohmura K, Momohara S, Mimori T, Yamanaka H, Kamatani N, Yamada R, Nakamura Y, Yamamoto K. Myouzen K, et al. Among authors: okada y. PLoS Genet. 2012 Sep;8(9):e1002949. doi: 10.1371/journal.pgen.1002949. Epub 2012 Sep 13. PLoS Genet. 2012. PMID: 23028356 Free PMC article.
Genome-wide association studies in the Japanese population identify seven novel loci for type 2 diabetes.
Imamura M, Takahashi A, Yamauchi T, Hara K, Yasuda K, Grarup N, Zhao W, Wang X, Huerta-Chagoya A, Hu C, Moon S, Long J, Kwak SH, Rasheed A, Saxena R, Ma RC, Okada Y, Iwata M, Hosoe J, Shojima N, Iwasaki M, Fujita H, Suzuki K, Danesh J, Jørgensen T, Jørgensen ME, Witte DR, Brandslund I, Christensen C, Hansen T, Mercader JM, Flannick J, Moreno-Macías H, Burtt NP, Zhang R, Kim YJ, Zheng W, Singh JR, Tam CH, Hirose H, Maegawa H, Ito C, Kaku K, Watada H, Tanaka Y, Tobe K, Kawamori R, Kubo M, Cho YS, Chan JC, Sanghera D, Frossard P, Park KS, Shu XO, Kim BJ, Florez JC, Tusié-Luna T, Jia W, Tai ES, Pedersen O, Saleheen D, Maeda S, Kadowaki T. Imamura M, et al. Among authors: okada y. Nat Commun. 2016 Jan 28;7:10531. doi: 10.1038/ncomms10531. Nat Commun. 2016. PMID: 26818947 Free PMC article.
Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis.
Ishigaki K, Kochi Y, Suzuki A, Tsuchida Y, Tsuchiya H, Sumitomo S, Yamaguchi K, Nagafuchi Y, Nakachi S, Kato R, Sakurai K, Shoda H, Ikari K, Taniguchi A, Yamanaka H, Miya F, Tsunoda T, Okada Y, Momozawa Y, Kamatani Y, Yamada R, Kubo M, Fujio K, Yamamoto K. Ishigaki K, et al. Among authors: okada y. Nat Genet. 2017 Jul;49(7):1120-1125. doi: 10.1038/ng.3885. Epub 2017 May 29. Nat Genet. 2017. PMID: 28553958
Genetic and phenotypic landscape of the major histocompatibilty complex region in the Japanese population.
Hirata J, Hosomichi K, Sakaue S, Kanai M, Nakaoka H, Ishigaki K, Suzuki K, Akiyama M, Kishikawa T, Ogawa K, Masuda T, Yamamoto K, Hirata M, Matsuda K, Momozawa Y, Inoue I, Kubo M, Kamatani Y, Okada Y. Hirata J, et al. Among authors: okada y. Nat Genet. 2019 Mar;51(3):470-480. doi: 10.1038/s41588-018-0336-0. Epub 2019 Jan 28. Nat Genet. 2019. PMID: 30692682
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
Suzuki K, Akiyama M, Ishigaki K, Kanai M, Hosoe J, Shojima N, Hozawa A, Kadota A, Kuriki K, Naito M, Tanno K, Ishigaki Y, Hirata M, Matsuda K, Iwata N, Ikeda M, Sawada N, Yamaji T, Iwasaki M, Ikegawa S, Maeda S, Murakami Y, Wakai K, Tsugane S, Sasaki M, Yamamoto M, Okada Y, Kubo M, Kamatani Y, Horikoshi M, Yamauchi T, Kadowaki T. Suzuki K, et al. Among authors: okada y. Nat Genet. 2019 Mar;51(3):379-386. doi: 10.1038/s41588-018-0332-4. Epub 2019 Feb 4. Nat Genet. 2019. PMID: 30718926
Next-generation sequencing identifies contribution of both class I and II HLA genes on susceptibility of multiple sclerosis in Japanese.
Ogawa K, Okuno T, Hosomichi K, Hosokawa A, Hirata J, Suzuki K, Sakaue S, Kinoshita M, Asano Y, Miyamoto K, Inoue I, Kusunoki S, Okada Y, Mochizuki H. Ogawa K, et al. Among authors: okada y. J Neuroinflammation. 2019 Aug 5;16(1):162. doi: 10.1186/s12974-019-1551-z. J Neuroinflammation. 2019. PMID: 31382992 Free PMC article.
7,099 results