Hoffman GE - Search Results

1

Large eQTL meta-analysis reveals differing patterns between cerebral cortical and cerebellar brain regions.

Sieberts SK, Perumal TM, Carrasquillo MM, Allen M, Reddy JS, Hoffman GE, Dang KK, Calley J, Ebert PJ, Eddy J, Wang X, Greenwood AK, Mostafavi S; CommonMind Consortium (CMC); The AMP-AD Consortium; Omberg L, Peters MA, Logsdon BA, De Jager PL, Ertekin-Taner N, Mangravite LM. Sieberts SK, et al. Among authors: hoffman ge. Sci Data. 2020 Oct 12;7(1):340. doi: 10.1038/s41597-020-00642-8. Sci Data. 2020. PMID: 33046718 Free PMC article.

2

A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis.

Logsdon BA, Hoffman GE, Mezey JG. Logsdon BA, et al. Among authors: hoffman ge. BMC Bioinformatics. 2010 Jan 27;11:58. doi: 10.1186/1471-2105-11-58. BMC Bioinformatics. 2010. PMID: 20105321 Free PMC article.

3

Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control.

Logsdon BA, Hoffman GE, Mezey JG. Logsdon BA, et al. Among authors: hoffman ge. BMC Bioinformatics. 2012 Apr 2;13:53. doi: 10.1186/1471-2105-13-53. BMC Bioinformatics. 2012. PMID: 22471599 Free PMC article.

4

PUMA: a unified framework for penalized multiple regression analysis of GWAS data.

Hoffman GE, Logsdon BA, Mezey JG. Hoffman GE, et al. PLoS Comput Biol. 2013;9(6):e1003101. doi: 10.1371/journal.pcbi.1003101. Epub 2013 Jun 27. PLoS Comput Biol. 2013. PMID: 23825936 Free PMC article.

5

lrgpr: interactive linear mixed model analysis of genome-wide association studies with composite hypothesis testing and regression diagnostics in R.

Hoffman GE, Mezey JG, Schadt EE. Hoffman GE, et al. Bioinformatics. 2014 Nov 1;30(21):3134-5. doi: 10.1093/bioinformatics/btu435. Epub 2014 Jul 16. Bioinformatics. 2014. PMID: 25035399 Free PMC article.

6

Improved integrative framework combining association data with gene expression features to prioritize Crohn's disease genes.

Ning K, Gettler K, Zhang W, Ng SM, Bowen BM, Hyams J, Stephens MC, Kugathasan S, Denson LA, Schadt EE, Hoffman GE, Cho JH. Ning K, et al. Among authors: hoffman ge. Hum Mol Genet. 2015 Jul 15;24(14):4147-57. doi: 10.1093/hmg/ddv142. Epub 2015 May 1. Hum Mol Genet. 2015. PMID: 25935003 Free PMC article.

7

variancePartition: interpreting drivers of variation in complex gene expression studies.

Hoffman GE, Schadt EE. Hoffman GE, et al. BMC Bioinformatics. 2016 Nov 25;17(1):483. doi: 10.1186/s12859-016-1323-z. BMC Bioinformatics. 2016. PMID: 27884101 Free PMC article.

8

Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains.

Hoffman GE, Hartley BJ, Flaherty E, Ladran I, Gochman P, Ruderfer DM, Stahl EA, Rapoport J, Sklar P, Brennand KJ. Hoffman GE, et al. Nat Commun. 2017 Dec 20;8(1):2225. doi: 10.1038/s41467-017-02330-5. Nat Commun. 2017. PMID: 29263384 Free PMC article.

9

Mapping regulatory variants in hiPSC models.

Hoffman GE, Brennand KJ. Hoffman GE, et al. Nat Genet. 2018 Jan;50(1):1-2. doi: 10.1038/s41588-017-0017-4. Nat Genet. 2018. PMID: 29273803 No abstract available.

10

New considerations for hiPSC-based models of neuropsychiatric disorders.

Hoffman GE, Schrode N, Flaherty E, Brennand KJ. Hoffman GE, et al. Mol Psychiatry. 2019 Jan;24(1):49-66. doi: 10.1038/s41380-018-0029-1. Epub 2018 Feb 26. Mol Psychiatry. 2019. PMID: 29483625 Free PMC article. Review.

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