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Role of Human 15-Lipoxygenase-2 in the Biosynthesis of the Lipoxin Intermediate, 5S,15S-diHpETE, Implicated with the Altered Positional Specificity of Human 15-Lipoxygenase-1.
Perry SC, Horn T, Tourdot BE, Yamaguchi A, Kalyanaraman C, Conrad WS, Akinkugbe O, Holinstat M, Jacobson MP, Holman TR. Perry SC, et al. Among authors: horn t. Biochemistry. 2020 Oct 27;59(42):4118-4130. doi: 10.1021/acs.biochem.0c00622. Epub 2020 Oct 13. Biochemistry. 2020. PMID: 33048542 Free PMC article.
Human 15-LOX-1 active site mutations alter inhibitor binding and decrease potency.
Armstrong M, van Hoorebeke C, Horn T, Deschamps J, Freedman JC, Kalyanaraman C, Jacobson MP, Holman T. Armstrong M, et al. Among authors: horn t. Bioorg Med Chem. 2016 Nov 1;24(21):5380-5387. doi: 10.1016/j.bmc.2016.08.063. Epub 2016 Aug 31. Bioorg Med Chem. 2016. PMID: 27647374 Free PMC article.
774 results