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5,350 results

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Page 1
Examination of Metoprolol Pharmacokinetics and Pharmacodynamics Across CYP2D6 Genotype-Derived Activity Scores.
Thomas CD, Mosley SA, Kim S, Lingineni K, El Rouby N, Langaee TY, Gong Y, Wang D, Schmidt SO, Binkley PF, Estores DS, Feng K, Kim H, Kinjo M, Li Z, Fang L, Chapman AB, Cooper-DeHoff RM, Gums JG, Hamadeh IS, Zhao L, Schmidt S, Frye RF, Johnson JA, Cavallari LH. Thomas CD, et al. Among authors: schmidt so, schmidt s. CPT Pharmacometrics Syst Pharmacol. 2020 Dec;9(12):678-685. doi: 10.1002/psp4.12563. Epub 2020 Nov 3. CPT Pharmacometrics Syst Pharmacol. 2020. PMID: 33067866 Free PMC article. Clinical Trial.
Predictors for glucose change in hypertensive participants following short-term treatment with atenolol or hydrochlorothiazide.
Moore MJ, Gong Y, Hou W, Hall K, Schmidt SO, Curry RW Jr, Beitelshees AL, Chapman A, Turner ST, Schwartz GL, Bailey K, Boerwinkle E, Gums JG, Cooper-DeHoff RM, Johnson JA. Moore MJ, et al. Pharmacotherapy. 2014 Nov;34(11):1132-40. doi: 10.1002/phar.1483. Epub 2014 Sep 9. Pharmacotherapy. 2014. PMID: 25202885 Free PMC article. Clinical Trial.
PTPRD gene associated with blood pressure response to atenolol and resistant hypertension.
Gong Y, McDonough CW, Beitelshees AL, El Rouby N, Hiltunen TP, O'Connell JR, Padmanabhan S, Langaee TY, Hall K, Schmidt SO, Curry RW Jr, Gums JG, Donner KM, Kontula KK, Bailey KR, Boerwinkle E, Takahashi A, Tanaka T, Kubo M, Chapman AB, Turner ST, Pepine CJ, Cooper-DeHoff RM, Johnson JA. Gong Y, et al. Among authors: schmidt so. J Hypertens. 2015 Nov;33(11):2278-85. doi: 10.1097/HJH.0000000000000714. J Hypertens. 2015. PMID: 26425837 Free PMC article.
Pharmacogenomic Genome-Wide Meta-Analysis of Blood Pressure Response to β-Blockers in Hypertensive African Americans.
Gong Y, Wang Z, Beitelshees AL, McDonough CW, Langaee TY, Hall K, Schmidt SO, Curry RW Jr, Gums JG, Bailey KR, Boerwinkle E, Chapman AB, Turner ST, Cooper-DeHoff RM, Johnson JA. Gong Y, et al. Hypertension. 2016 Mar;67(3):556-63. doi: 10.1161/HYPERTENSIONAHA.115.06345. Epub 2016 Jan 4. Hypertension. 2016. PMID: 26729753 Free PMC article.
CYP2D6-guided opioid therapy improves pain control in CYP2D6 intermediate and poor metabolizers: a pragmatic clinical trial.
Smith DM, Weitzel KW, Elsey AR, Langaee T, Gong Y, Wake DT, Duong BQ, Hagen M, Harle CA, Mercado E, Nagoshi Y, Newsom K, Wright A, Rosenberg EI, Starostik P, Clare-Salzler MJ, Schmidt SO, Fillingim RB, Johnson JA, Cavallari LH. Smith DM, et al. Genet Med. 2019 Aug;21(8):1842-1850. doi: 10.1038/s41436-018-0431-8. Epub 2019 Jan 23. Genet Med. 2019. PMID: 30670877 Free PMC article. Clinical Trial.
Challenges and lessons learned from clinical pharmacogenetic implementation of multiple gene-drug pairs across ambulatory care settings.
Cicali EJ, Weitzel KW, Elsey AR, Orlando FA, Vinson M, Mosley S, Smith DM, Davis R, Drum L, Estores D, Franciosi JP, Hagen MG, Jerkins GJ, Mercado ES, Nainaparampil J, Padron A, Rosenberg EI, Wright A, Schmidt SO, Mathews CA, Cavallari LH, Johnson JA. Cicali EJ, et al. Among authors: schmidt so. Genet Med. 2019 Oct;21(10):2264-2274. doi: 10.1038/s41436-019-0500-7. Epub 2019 Mar 30. Genet Med. 2019. PMID: 30926959 Free PMC article.
Determining the potential clinical value of panel-based pharmacogenetic testing in patients with chronic pain or gastroesophageal reflux disease.
Elchynski AL, Cicali EJ, Ferrer Del Busto MC, Hamilton A, Chang KL, Schmidt SO, Weiner B, Davis R, Estores D, Max Smith D, Wiisanen K, Johnson JA, Cavallari LH. Elchynski AL, et al. Pharmacogenomics J. 2021 Dec;21(6):657-663. doi: 10.1038/s41397-021-00244-6. Epub 2021 Jun 1. Pharmacogenomics J. 2021. PMID: 34075203 Free PMC article.
A randomized, cross-over trial of metoprolol succinate formulations to evaluate PK and PD end points for therapeutic equivalence.
Mosley SA, Kim S, El Rouby N, Lingineni K, Esteban VV, Gong Y, Chen Y, Estores D, Feng K, Kim H, Kinjo M, Langaee T, Li Z, Schmidt SOF, Johnson JA, Frye RF, Fang LL, Zhao L, Binkley PF, Schmidt S, Cavallari LH. Mosley SA, et al. Among authors: schmidt s, schmidt sof. Clin Transl Sci. 2022 Jul;15(7):1764-1775. doi: 10.1111/cts.13294. Epub 2022 May 21. Clin Transl Sci. 2022. PMID: 35488487 Free PMC article. Clinical Trial.
5,350 results