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Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1-42.
Kober DL, Stuchell-Brereton MD, Kluender CE, Dean HB, Strickland MR, Steinberg DF, Nelson SS, Baban B, Holtzman DM, Frieden C, Alexander-Brett J, Roberson ED, Song Y, Brett TJ. Kober DL, et al. Among authors: stuchell brereton md. Alzheimers Dement. 2020 Oct 8:10.1002/alz.12194. doi: 10.1002/alz.12194. Online ahead of print. Alzheimers Dement. 2020. PMID: 33090700 Free PMC article.
Apolipoprotein E4 has extensive conformational heterogeneity in lipid-free and lipid-bound forms.
Stuchell-Brereton MD, Zimmerman MI, Miller JJ, Mallimadugula UL, Incicco JJ, Roy D, Smith LG, Cubuk J, Baban B, DeKoster GT, Frieden C, Bowman GR, Soranno A. Stuchell-Brereton MD, et al. Proc Natl Acad Sci U S A. 2023 Feb 14;120(7):e2215371120. doi: 10.1073/pnas.2215371120. Epub 2023 Feb 7. Proc Natl Acad Sci U S A. 2023. PMID: 36749730 Free PMC article.
Biophysical Mechanism of Allosteric Regulation of Actin Capping Protein.
Mooren OL, Stuchell-Brereton MD, McConnell P, Yan C, Wilkerson EM, Goldfarb D, Cooper JA, Sept D, Soranno A. Mooren OL, et al. Among authors: stuchell brereton md. J Mol Biol. 2023 Dec 15;435(24):168342. doi: 10.1016/j.jmb.2023.168342. Epub 2023 Nov 2. J Mol Biol. 2023. PMID: 37924863
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.
Cubuk J, Alston JJ, Incicco JJ, Singh S, Stuchell-Brereton MD, Ward MD, Zimmerman MI, Vithani N, Griffith D, Wagoner JA, Bowman GR, Hall KB, Soranno A, Holehouse AS. Cubuk J, et al. Among authors: stuchell brereton md. Nat Commun. 2021 Mar 29;12(1):1936. doi: 10.1038/s41467-021-21953-3. Nat Commun. 2021. PMID: 33782395 Free PMC article.
The SARS-CoV-2 nucleocapsid protein is dynamic, disordered, and phase separates with RNA.
Cubuk J, Alston JJ, Incicco JJ, Singh S, Stuchell-Brereton MD, Ward MD, Zimmerman MI, Vithani N, Griffith D, Wagoner JA, Bowman GR, Hall KB, Soranno A, Holehouse AS. Cubuk J, et al. Among authors: stuchell brereton md. bioRxiv [Preprint]. 2020 Dec 21:2020.06.17.158121. doi: 10.1101/2020.06.17.158121. bioRxiv. 2020. PMID: 32587966 Free PMC article. Updated. Preprint.
Fluorescence Correlation Spectroscopy and Phase Separation.
Incicco JJ, Roy D, Stuchell-Brereton MD, Soranno A. Incicco JJ, et al. Among authors: stuchell brereton md. Methods Mol Biol. 2023;2563:161-198. doi: 10.1007/978-1-0716-2663-4_8. Methods Mol Biol. 2023. PMID: 36227473
14 results