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AXL Is a Driver of Stemness in Normal Mammary Gland and Breast Cancer.
Engelsen AST, Wnuk-Lipinska K, Bougnaud S, Pelissier Vatter FA, Tiron C, Villadsen R, Miyano M, Lotsberg ML, Madeleine N, Panahandeh P, Dhakal S, Tan TZ, Peters SD, Grøndal S, Aziz SM, Nord S, Herfindal L, Stampfer MR, Sørlie T, Brekken RA, Straume O, Halberg N, Gausdal G, Thiery JP, Akslen LA, Petersen OW, LaBarge MA, Lorens JB. Engelsen AST, et al. Among authors: brekken ra. iScience. 2020 Oct 7;23(11):101649. doi: 10.1016/j.isci.2020.101649. eCollection 2020 Nov 20. iScience. 2020. PMID: 33103086 Free PMC article.
A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics.
Ocal O, Pashkov V, Kollipara RK, Zolghadri Y, Cruz VH, Hale MA, Heath BR, Artyukhin AB, Christie AL, Tsoulfas P, Lorens JB, Swift GH, Brekken RA, Wilkie TM. Ocal O, et al. Among authors: brekken ra. Dis Model Mech. 2015 Oct 1;8(10):1201-11. doi: 10.1242/dmm.020933. Dis Model Mech. 2015. PMID: 26438693 Free PMC article.
AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells.
Lotsberg ML, Wnuk-Lipinska K, Terry S, Tan TZ, Lu N, Trachsel-Moncho L, Røsland GV, Siraji MI, Hellesøy M, Rayford A, Jacobsen K, Ditzel HJ, Vintermyr OK, Bivona TG, Minna J, Brekken RA, Baguley B, Micklem D, Akslen LA, Gausdal G, Simonsen A, Thiery JP, Chouaib S, Lorens JB, Engelsen AST. Lotsberg ML, et al. Among authors: brekken ra. J Thorac Oncol. 2020 Jun;15(6):973-999. doi: 10.1016/j.jtho.2020.01.015. Epub 2020 Feb 1. J Thorac Oncol. 2020. PMID: 32018052 Free PMC article.
High-dimensional immunotyping of tumors grown in obese and non-obese mice.
Wogsland CE, Lien HE, Pedersen L, Hanjra P, Grondal SM, Brekken RA, Lorens JB, Halberg N. Wogsland CE, et al. Among authors: brekken ra. Dis Model Mech. 2021 Apr 1;14(4):dmm048977. doi: 10.1242/dmm.048977. Epub 2021 Mar 30. Dis Model Mech. 2021. PMID: 33653826 Free PMC article.
AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells.
Li H, Liu Z, Liu L, Zhang H, Han C, Girard L, Park H, Zhang A, Dong C, Ye J, Rayford A, Peyton M, Li X, Avila K, Cao X, Hu S, Alam MM, Akbay EA, Solis LM, Behrens C, Hernandez-Ruiz S, Lu W, Wistuba I, Heymach JV, Chisamore M, Micklem D, Gabra H, Gausdal G, Lorens JB, Li B, Fu YX, Minna JD, Brekken RA. Li H, et al. Among authors: brekken ra. Cell Rep Med. 2022 Mar 15;3(3):100554. doi: 10.1016/j.xcrm.2022.100554. eCollection 2022 Mar 15. Cell Rep Med. 2022. PMID: 35492873 Free PMC article.
PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression.
Sui L, Wang S, Ganguly D, El Rayes TP, Askeland C, Børretzen A, Sim D, Halvorsen OJ, Knutsvik G, Arnes J, Aziz S, Haukaas S, Foulkes WD, Bielenberg DR, Ziemys A, Mittal V, Brekken RA, Akslen LA, Watnick RS. Sui L, et al. Among authors: brekken ra. Nat Commun. 2022 Dec 27;13(1):7959. doi: 10.1038/s41467-022-35649-9. Nat Commun. 2022. PMID: 36575174 Free PMC article.
229 results