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Cancer therapy shapes the fitness landscape of clonal hematopoiesis.
Bolton KL, Ptashkin RN, Gao T, Braunstein L, Devlin SM, Kelly D, Patel M, Berthon A, Syed A, Yabe M, Coombs CC, Caltabellotta NM, Walsh M, Offit K, Stadler Z, Mandelker D, Schulman J, Patel A, Philip J, Bernard E, Gundem G, Ossa JEA, Levine M, Martinez JSM, Farnoud N, Glodzik D, Li S, Robson ME, Lee C, Pharoah PDP, Stopsack KH, Spitzer B, Mantha S, Fagin J, Boucai L, Gibson CJ, Ebert BL, Young AL, Druley T, Takahashi K, Gillis N, Ball M, Padron E, Hyman DM, Baselga J, Norton L, Gardos S, Klimek VM, Scher H, Bajorin D, Paraiso E, Benayed R, Arcila ME, Ladanyi M, Solit DB, Berger MF, Tallman M, Garcia-Closas M, Chatterjee N, Diaz LA Jr, Levine RL, Morton LM, Zehir A, Papaemmanuil E. Bolton KL, et al. Among authors: takahashi k. Nat Genet. 2020 Nov;52(11):1219-1226. doi: 10.1038/s41588-020-00710-0. Epub 2020 Oct 26. Nat Genet. 2020. PMID: 33106634 Free PMC article.
Emerging patterns of somatic mutations in cancer.
Watson IR, Takahashi K, Futreal PA, Chin L. Watson IR, et al. Among authors: takahashi k. Nat Rev Genet. 2013 Oct;14(10):703-18. doi: 10.1038/nrg3539. Epub 2013 Sep 11. Nat Rev Genet. 2013. PMID: 24022702 Free PMC article. Review.
Acute promyelocytic leukemia presented as a relapse of acute myeloid leukemia.
Vitale C, Jabbour E, Lu X, Yabe M, Kanagal Shamanna R, Daver N, Pemmaraju N, Bueso-Ramos CE, Takahashi K. Vitale C, et al. Among authors: takahashi k. Am J Hematol. 2016 Jun;91(4):E274-6. doi: 10.1002/ajh.24302. Epub 2016 Feb 29. Am J Hematol. 2016. PMID: 26798971 Free article. No abstract available.
Preleukaemic clonal haemopoiesis and risk of therapy-related myeloid neoplasms: a case-control study.
Takahashi K, Wang F, Kantarjian H, Doss D, Khanna K, Thompson E, Zhao L, Patel K, Neelapu S, Gumbs C, Bueso-Ramos C, DiNardo CD, Colla S, Ravandi F, Zhang J, Huang X, Wu X, Samaniego F, Garcia-Manero G, Futreal PA. Takahashi K, et al. Lancet Oncol. 2017 Jan;18(1):100-111. doi: 10.1016/S1470-2045(16)30626-X. Epub 2016 Dec 3. Lancet Oncol. 2017. PMID: 27923552 Free PMC article.
Integrative genomic analysis of adult mixed phenotype acute leukemia delineates lineage associated molecular subtypes.
Takahashi K, Wang F, Morita K, Yan Y, Hu P, Zhao P, Zhar AA, Wu CJ, Gumbs C, Little L, Tippen S, Thornton R, Coyle M, Mendoza M, Thompson E, Zhang J, DiNardo CD, Jain N, Ravandi F, Cortes JE, Garcia-Manero G, Kornblau S, Andreeff M, Jabbour E, Bueso-Ramos C, Takaori-Kondo A, Konopleva M, Patel K, Kantarjian H, Futreal PA. Takahashi K, et al. Nat Commun. 2018 Jul 10;9(1):2670. doi: 10.1038/s41467-018-04924-z. Nat Commun. 2018. PMID: 29991687 Free PMC article.
PPM1D Mutations Drive Clonal Hematopoiesis in Response to Cytotoxic Chemotherapy.
Hsu JI, Dayaram T, Tovy A, De Braekeleer E, Jeong M, Wang F, Zhang J, Heffernan TP, Gera S, Kovacs JJ, Marszalek JR, Bristow C, Yan Y, Garcia-Manero G, Kantarjian H, Vassiliou G, Futreal PA, Donehower LA, Takahashi K, Goodell MA. Hsu JI, et al. Among authors: takahashi k. Cell Stem Cell. 2018 Nov 1;23(5):700-713.e6. doi: 10.1016/j.stem.2018.10.004. Cell Stem Cell. 2018. PMID: 30388424 Free PMC article.
Managing Clonal Hematopoiesis in Patients With Solid Tumors.
Bolton KL, Gillis NK, Coombs CC, Takahashi K, Zehir A, Bejar R, Garcia-Manero G, Futreal A, Jensen BC, Diaz LA Jr, Gupta D, Mantha S, Klimek V, Papaemmanuil E, Levine R, Padron E. Bolton KL, et al. Among authors: takahashi k. J Clin Oncol. 2019 Jan 1;37(1):7-11. doi: 10.1200/JCO.18.00331. Epub 2018 Nov 7. J Clin Oncol. 2019. PMID: 30403571 Free PMC article. No abstract available.
Late relapse in acute myeloid leukemia (AML): clonal evolution or therapy-related leukemia?
Yilmaz M, Wang F, Loghavi S, Bueso-Ramos C, Gumbs C, Little L, Song X, Zhang J, Kadia T, Borthakur G, Jabbour E, Pemmaraju N, Short N, Garcia-Manero G, Estrov Z, Kantarjian H, Futreal A, Takahashi K, Ravandi F. Yilmaz M, et al. Among authors: takahashi k. Blood Cancer J. 2019 Jan 16;9(2):7. doi: 10.1038/s41408-019-0170-3. Blood Cancer J. 2019. PMID: 30651532 Free PMC article.
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