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LabWAS: Novel findings and study design recommendations from a meta-analysis of clinical labs in two independent biobanks.
Goldstein JA, Weinstock JS, Bastarache LA, Larach DB, Fritsche LG, Schmidt EM, Brummett CM, Kheterpal S, Abecasis GR, Denny JC, Zawistowski M. Goldstein JA, et al. Among authors: larach db. PLoS Genet. 2020 Nov 11;16(11):e1009077. doi: 10.1371/journal.pgen.1009077. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33175840 Free PMC article.
Targeted exonic sequencing of GWAS loci in the high extremes of the plasma lipids distribution.
Patel AP, Peloso GM, Pirruccello JP, Johansen CT, Dubé JB, Larach DB, Ban MR, Dallinge-Thie GM, Gupta N, Boehnke M, Abecasis GR, Kastelein JJ, Hovingh GK, Hegele RA, Rader DJ, Kathiresan S. Patel AP, et al. Among authors: larach db. Atherosclerosis. 2016 Jul;250:63-8. doi: 10.1016/j.atherosclerosis.2016.04.011. Epub 2016 Apr 23. Atherosclerosis. 2016. PMID: 27182959 Free PMC article.
Sex-specific and pleiotropic effects underlying kidney function identified from GWAS meta-analysis.
Graham SE, Nielsen JB, Zawistowski M, Zhou W, Fritsche LG, Gabrielsen ME, Skogholt AH, Surakka I, Hornsby WE, Fermin D, Larach DB, Kheterpal S, Brummett CM, Lee S, Kang HM, Abecasis GR, Romundstad S, Hallan S, Sampson MG, Hveem K, Willer CJ. Graham SE, et al. Among authors: larach db. Nat Commun. 2019 Apr 23;10(1):1847. doi: 10.1038/s41467-019-09861-z. Nat Commun. 2019. PMID: 31015462 Free PMC article.
Limited clinical utility for GWAS or polygenic risk score for postoperative acute kidney injury in non-cardiac surgery in European-ancestry patients.
Larach DB, Lewis A, Bastarache L, Pandit A, He J, Sinha A, Douville NJ, Heung M, Mathis MR, Mosley JD, Wanderer JP, Kheterpal S, Zawistowski M, Brummett CM, Siew ED, Robinson-Cohen C, Kertai MD. Larach DB, et al. BMC Nephrol. 2022 Oct 21;23(1):339. doi: 10.1186/s12882-022-02964-8. BMC Nephrol. 2022. PMID: 36271344 Free PMC article.
22 results