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A Deep Learning Approach Validates Genetic Risk Factors for Late Toxicity After Prostate Cancer Radiotherapy in a REQUITE Multi-National Cohort.
Massi MC, Gasperoni F, Ieva F, Paganoni AM, Zunino P, Manzoni A, Franco NR, Veldeman L, Ost P, Fonteyne V, Talbot CJ, Rattay T, Webb A, Symonds PR, Johnson K, Lambrecht M, Haustermans K, De Meerleer G, de Ruysscher D, Vanneste B, Van Limbergen E, Choudhury A, Elliott RM, Sperk E, Herskind C, Veldwijk MR, Avuzzi B, Giandini T, Valdagni R, Cicchetti A, Azria D, Jacquet MF, Rosenstein BS, Stock RG, Collado K, Vega A, Aguado-Barrera ME, Calvo P, Dunning AM, Fachal L, Kerns SL, Payne D, Chang-Claude J, Seibold P, West CML, Rancati T. Massi MC, et al. Among authors: franco nr. Front Oncol. 2020 Oct 15;10:541281. doi: 10.3389/fonc.2020.541281. eCollection 2020. Front Oncol. 2020. PMID: 33178576 Free PMC article.
Development of a method for generating SNP interaction-aware polygenic risk scores for radiotherapy toxicity.
Franco NR, Massi MC, Ieva F, Manzoni A, Paganoni AM, Zunino P, Veldeman L, Ost P, Fonteyne V, Talbot CJ, Rattay T, Webb A, Johnson K, Lambrecht M, Haustermans K, De Meerleer G, de Ruysscher D, Vanneste B, Van Limbergen E, Choudhury A, Elliott RM, Sperk E, Veldwijk MR, Herskind C, Avuzzi B, Noris Chiorda B, Valdagni R, Azria D, Farcy-Jacquet MP, Brengues M, Rosenstein BS, Stock RG, Vega A, Aguado-Barrera ME, Sosa-Fajardo P, Dunning AM, Fachal L, Kerns SL, Payne D, Chang-Claude J, Seibold P, West CML, Rancati T; REQUITE Consortium Collaborators. Franco NR, et al. Radiother Oncol. 2021 Jun;159:241-248. doi: 10.1016/j.radonc.2021.03.024. Epub 2021 Apr 8. Radiother Oncol. 2021. PMID: 33838170 Free PMC article.
Learning high-order interactions for polygenic risk prediction.
Massi MC, Franco NR, Manzoni A, Paganoni AM, Park HA, Hoffmeister M, Brenner H, Chang-Claude J, Ieva F, Zunino P. Massi MC, et al. Among authors: franco nr. PLoS One. 2023 Feb 10;18(2):e0281618. doi: 10.1371/journal.pone.0281618. eCollection 2023. PLoS One. 2023. PMID: 36763605 Free PMC article.
Novel mutations in breast cancer patients from southwestern Colombia.
Solarte M, Cortes-Urrea C, Franco NR, Barreto G, Moreno PA. Solarte M, et al. Among authors: franco nr. Genet Mol Biol. 2020 Nov 18;43(4):e20190359. doi: 10.1590/1678-4685-GMB-2019-0359. eCollection 2020. Genet Mol Biol. 2020. PMID: 33231602 Free PMC article.
Loss of hepatic PPARα promotes inflammation and serum hyperlipidemia in diet-induced obesity.
Stec DE, Gordon DM, Hipp JA, Hong S, Mitchell ZL, Franco NR, Robison JW, Anderson CD, Stec DF, Hinds TD Jr. Stec DE, et al. Among authors: franco nr. Am J Physiol Regul Integr Comp Physiol. 2019 Nov 1;317(5):R733-R745. doi: 10.1152/ajpregu.00153.2019. Epub 2019 Sep 4. Am J Physiol Regul Integr Comp Physiol. 2019. PMID: 31483154 Free PMC article.