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Functional investigation of the coronary artery disease gene SVEP1.
Winkler MJ, Müller P, Sharifi AM, Wobst J, Winter H, Mokry M, Ma L, van der Laan SW, Pang S, Miritsch B, Hinterdobler J, Werner J, Stiller B, Güldener U, Webb TR, Asselbergs FW, Björkegren JLM, Maegdefessel L, Schunkert H, Sager HB, Kessler T. Winkler MJ, et al. Among authors: maegdefessel l. Basic Res Cardiol. 2020 Nov 13;115(6):67. doi: 10.1007/s00395-020-00828-6. Basic Res Cardiol. 2020. PMID: 33185739 Free PMC article.
Coronary heart disease-associated variation in TCF21 disrupts a miR-224 binding site and miRNA-mediated regulation.
Miller CL, Haas U, Diaz R, Leeper NJ, Kundu RK, Patlolla B, Assimes TL, Kaiser FJ, Perisic L, Hedin U, Maegdefessel L, Schunkert H, Erdmann J, Quertermous T, Sczakiel G. Miller CL, et al. Among authors: maegdefessel l. PLoS Genet. 2014 Mar 27;10(3):e1004263. doi: 10.1371/journal.pgen.1004263. eCollection 2014 Mar. PLoS Genet. 2014. PMID: 24676100 Free PMC article.
Local Delivery of miR-21 Stabilizes Fibrous Caps in Vulnerable Atherosclerotic Lesions.
Jin H, Li DY, Chernogubova E, Sun C, Busch A, Eken SM, Saliba-Gustafsson P, Winter H, Winski G, Raaz U, Schellinger IN, Simon N, Hegenloh R, Matic LP, Jagodic M, Ehrenborg E, Pelisek J, Eckstein HH, Hedin U, Backlund A, Maegdefessel L. Jin H, et al. Among authors: maegdefessel l. Mol Ther. 2018 Apr 4;26(4):1040-1055. doi: 10.1016/j.ymthe.2018.01.011. Epub 2018 Jan 31. Mol Ther. 2018. PMID: 29503197 Free PMC article.
miR-29b Mediates the Chronic Inflammatory Response in Radiotherapy-Induced Vascular Disease.
Eken SM, Christersdottir T, Winski G, Sangsuwan T, Jin H, Chernogubova E, Pirault J, Sun C, Simon N, Winter H, Backlund A, Haghdoost S, Hansson GK, Halle M, Maegdefessel L. Eken SM, et al. Among authors: maegdefessel l. JACC Basic Transl Sci. 2019 Feb 25;4(1):72-82. doi: 10.1016/j.jacbts.2018.10.006. eCollection 2019 Feb. JACC Basic Transl Sci. 2019. PMID: 30847421 Free PMC article.
Externalized histone H4 orchestrates chronic inflammation by inducing lytic cell death.
Silvestre-Roig C, Braster Q, Wichapong K, Lee EY, Teulon JM, Berrebeh N, Winter J, Adrover JM, Santos GS, Froese A, Lemnitzer P, Ortega-Gómez A, Chevre R, Marschner J, Schumski A, Winter C, Perez-Olivares L, Pan C, Paulin N, Schoufour T, Hartwig H, González-Ramos S, Kamp F, Megens RTA, Mowen KA, Gunzer M, Maegdefessel L, Hackeng T, Lutgens E, Daemen M, von Blume J, Anders HJ, Nikolaev VO, Pellequer JL, Weber C, Hidalgo A, Nicolaes GAF, Wong GCL, Soehnlein O. Silvestre-Roig C, et al. Among authors: maegdefessel l. Nature. 2019 May;569(7755):236-240. doi: 10.1038/s41586-019-1167-6. Epub 2019 May 1. Nature. 2019. PMID: 31043745 Free PMC article.
Non-coding RNAs in cardiovascular cell biology and atherosclerosis.
Fasolo F, Di Gregoli K, Maegdefessel L, Johnson JL. Fasolo F, et al. Among authors: maegdefessel l. Cardiovasc Res. 2019 Oct 1;115(12):1732-1756. doi: 10.1093/cvr/cvz203. Cardiovasc Res. 2019. PMID: 31389987 Free PMC article. Review.
Clonally expanding smooth muscle cells promote atherosclerosis by escaping efferocytosis and activating the complement cascade.
Wang Y, Nanda V, Direnzo D, Ye J, Xiao S, Kojima Y, Howe KL, Jarr KU, Flores AM, Tsantilas P, Tsao N, Rao A, Newman AAC, Eberhard AV, Priest JR, Ruusalepp A, Pasterkamp G, Maegdefessel L, Miller CL, Lind L, Koplev S, Björkegren JLM, Owens GK, Ingelsson E, Weissman IL, Leeper NJ. Wang Y, et al. Among authors: maegdefessel l. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15818-15826. doi: 10.1073/pnas.2006348117. Epub 2020 Jun 15. Proc Natl Acad Sci U S A. 2020. PMID: 32541024 Free PMC article.
Chitinase 3 like 1 is a regulator of smooth muscle cell physiology and atherosclerotic lesion stability.
Tsantilas P, Lao S, Wu Z, Eberhard A, Winski G, Vaerst M, Nanda V, Wang Y, Kojima Y, Ye J, Flores A, Jarr KU, Pelisek J, Eckstein HH, Matic L, Hedin U, Tsao PS, Paloschi V, Maegdefessel L, Leeper NJ. Tsantilas P, et al. Among authors: maegdefessel l. Cardiovasc Res. 2021 Dec 17;117(14):2767-2780. doi: 10.1093/cvr/cvab014. Cardiovasc Res. 2021. PMID: 33471078 Free PMC article.
175 results