Luijten M - Search Results

1

Mutagenicity of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine (N-OH-PhIP) in human TP53 knock-in (Hupki) mouse embryo fibroblasts.

Hölzl-Armstrong L, Moody S, Kucab JE, Zwart EP, Bellamri M, Luijten M, Turesky RJ, Stratton MR, Arlt VM, Phillips DH. Hölzl-Armstrong L, et al. Among authors: luijten m. Food Chem Toxicol. 2021 Jan;147:111855. doi: 10.1016/j.fct.2020.111855. Epub 2020 Nov 12. Food Chem Toxicol. 2021. PMID: 33189884

2

Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro.

Zwart EP, Schaap MM, van den Dungen MW, Braakhuis HM, White PA, van Steeg H, van Benthem J, Luijten M. Zwart EP, et al. Among authors: luijten m. Environ Mol Mutagen. 2012 Jun;53(5):1-8. doi: 10.1002/em.21700. Epub 2012 May 23. Environ Mol Mutagen. 2012. PMID: 22619112

3

Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes.

Schaap MM, Zwart EP, Wackers PF, Huijskens I, van de Water B, Breit TM, van Steeg H, Jonker MJ, Luijten M. Schaap MM, et al. Among authors: luijten m. Arch Toxicol. 2012 Nov;86(11):1717-27. doi: 10.1007/s00204-012-0883-6. Epub 2012 Jun 19. Arch Toxicol. 2012. PMID: 22710402

4

Slow accumulation of mutations in Xpc-/- mice upon induction of oxidative stress.

Melis JP, Kuiper RV, Zwart E, Robinson J, Pennings JL, van Oostrom CT, Luijten M, van Steeg H. Melis JP, et al. Among authors: luijten m. DNA Repair (Amst). 2013 Dec;12(12):1081-6. doi: 10.1016/j.dnarep.2013.08.019. Epub 2013 Sep 29. DNA Repair (Amst). 2013. PMID: 24084170 Free PMC article.

5

In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals.

Melis JP, Derks KW, Pronk TE, Wackers P, Schaap MM, Zwart E, van Ijcken WF, Jonker MJ, Breit TM, Pothof J, van Steeg H, Luijten M. Melis JP, et al. Among authors: luijten m. Arch Toxicol. 2014 Apr;88(4):1023-34. doi: 10.1007/s00204-013-1189-z. Epub 2014 Jan 5. Arch Toxicol. 2014. PMID: 24390151

6

A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens.

Schaap MM, Wackers PF, Zwart EP, Huijskens I, Jonker MJ, Hendriks G, Breit TM, van Steeg H, van de Water B, Luijten M. Schaap MM, et al. Among authors: luijten m. Arch Toxicol. 2015 Dec;89(12):2413-27. doi: 10.1007/s00204-014-1368-6. Epub 2014 Oct 2. Arch Toxicol. 2015. PMID: 25270620

7

TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.

Kucab JE, van Steeg H, Luijten M, Schmeiser HH, White PA, Phillips DH, Arlt VM. Kucab JE, et al. Among authors: luijten m. Mutat Res. 2015 Mar;773:48-62. doi: 10.1016/j.mrfmmm.2015.01.013. Epub 2015 Jan 30. Mutat Res. 2015. PMID: 25847421 Free PMC article.

8

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice.

Krais AM, Speksnijder EN, Melis JP, Indra R, Moserova M, Godschalk RW, van Schooten FJ, Seidel A, Kopka K, Schmeiser HH, Stiborova M, Phillips DH, Luijten M, Arlt VM. Krais AM, et al. Among authors: luijten m. Arch Toxicol. 2016 Apr;90(4):839-51. doi: 10.1007/s00204-015-1531-8. Epub 2015 May 21. Arch Toxicol. 2016. PMID: 25995008 Free PMC article.

9

Metabolic activation of 2-amino-1-methyl-6-phenylimidazo [4,5-b]pyridine and DNA adduct formation depends on p53: Studies in Trp53(+/+),Trp53(+/-) and Trp53(-/-) mice.

Krais AM, Speksnijder EN, Melis JP, Singh R, Caldwell A, Gamboa da Costa G, Luijten M, Phillips DH, Arlt VM. Krais AM, et al. Among authors: luijten m. Int J Cancer. 2016 Feb 15;138(4):976-82. doi: 10.1002/ijc.29836. Epub 2015 Sep 22. Int J Cancer. 2016. PMID: 26335255 Free PMC article.

10

TP53 and lacZ mutagenesis induced by 3-nitrobenzanthrone in Xpa-deficient human TP53 knock-in mouse embryo fibroblasts.

Kucab JE, Zwart EP, van Steeg H, Luijten M, Schmeiser HH, Phillips DH, Arlt VM. Kucab JE, et al. Among authors: luijten m. DNA Repair (Amst). 2016 Mar;39:21-33. doi: 10.1016/j.dnarep.2015.11.004. Epub 2015 Dec 8. DNA Repair (Amst). 2016. PMID: 26723900 Free PMC article.

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