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Evidence for linkage of pfmdr1, pfcrt, and pfk13 polymorphisms to lumefantrine and mefloquine susceptibilities in a Plasmodium falciparum cross.
Windle ST, Lane KD, Gadalla NB, Liu A, Mu J, Caleon RL, Rahman RS, Sá JM, Wellems TE. Windle ST, et al. Among authors: gadalla nb. Int J Parasitol Drugs Drug Resist. 2020 Dec;14:208-217. doi: 10.1016/j.ijpddr.2020.10.009. Epub 2020 Oct 27. Int J Parasitol Drugs Drug Resist. 2020. PMID: 33197753 Free PMC article.
Directional selection at the pfmdr1, pfcrt, pfubp1, and pfap2mu loci of Plasmodium falciparum in Kenyan children treated with ACT.
Henriques G, Hallett RL, Beshir KB, Gadalla NB, Johnson RE, Burrow R, van Schalkwyk DA, Sawa P, Omar SA, Clark TG, Bousema T, Sutherland CJ. Henriques G, et al. Among authors: gadalla nb. J Infect Dis. 2014 Dec 15;210(12):2001-8. doi: 10.1093/infdis/jiu358. Epub 2014 Jul 3. J Infect Dis. 2014. PMID: 24994911 Free PMC article.
Multiple Origins of Mutations in the mdr1 Gene--A Putative Marker of Chloroquine Resistance in P. vivax.
Schousboe ML, Ranjitkar S, Rajakaruna RS, Amerasinghe PH, Morales F, Pearce R, Ord R, Leslie T, Rowland M, Gadalla NB, Konradsen F, Bygbjerg IC, Roper C, Alifrangis M. Schousboe ML, et al. Among authors: gadalla nb. PLoS Negl Trop Dis. 2015 Nov 5;9(11):e0004196. doi: 10.1371/journal.pntd.0004196. eCollection 2015 Nov. PLoS Negl Trop Dis. 2015. PMID: 26539821 Free PMC article.
Increased pfmdr1 copy number and sequence polymorphisms in Plasmodium falciparum isolates from Sudanese malaria patients treated with artemether-lumefantrine.
Gadalla NB, Adam I, Elzaki SE, Bashir S, Mukhtar I, Oguike M, Gadalla A, Mansour F, Warhurst D, El-Sayed BB, Sutherland CJ. Gadalla NB, et al. Among authors: gadalla a. Antimicrob Agents Chemother. 2011 Nov;55(11):5408-11. doi: 10.1128/AAC.05102-11. Epub 2011 Sep 6. Antimicrob Agents Chemother. 2011. PMID: 21896916 Free PMC article.
Polymorphisms in Plasmodium falciparum chloroquine resistance transporter and multidrug resistance 1 genes: parasite risk factors that affect treatment outcomes for P. falciparum malaria after artemether-lumefantrine and artesunate-amodiaquine.
Venkatesan M, Gadalla NB, Stepniewska K, Dahal P, Nsanzabana C, Moriera C, Price RN, Mårtensson A, Rosenthal PJ, Dorsey G, Sutherland CJ, Guérin P, Davis TME, Ménard D, Adam I, Ademowo G, Arze C, Baliraine FN, Berens-Riha N, Björkman A, Borrmann S, Checchi F, Desai M, Dhorda M, Djimdé AA, El-Sayed BB, Eshetu T, Eyase F, Falade C, Faucher JF, Fröberg G, Grivoyannis A, Hamour S, Houzé S, Johnson J, Kamugisha E, Kariuki S, Kiechel JR, Kironde F, Kofoed PE, LeBras J, Malmberg M, Mwai L, Ngasala B, Nosten F, Nsobya SL, Nzila A, Oguike M, Otienoburu SD, Ogutu B, Ouédraogo JB, Piola P, Rombo L, Schramm B, Somé AF, Thwing J, Ursing J, Wong RPM, Zeynudin A, Zongo I, Plowe CV, Sibley CH, Asaq Molecular Marker Study Group. Venkatesan M, et al. Among authors: gadalla nb. Am J Trop Med Hyg. 2014 Oct;91(4):833-843. doi: 10.4269/ajtmh.14-0031. Epub 2014 Jul 21. Am J Trop Med Hyg. 2014. PMID: 25048375 Free PMC article.
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