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Targeting OGG1 arrests cancer cell proliferation by inducing replication stress.
Visnes T, Benítez-Buelga C, Cázares-Körner A, Sanjiv K, Hanna BMF, Mortusewicz O, Rajagopal V, Albers JJ, Hagey DW, Bekkhus T, Eshtad S, Baquero JM, Masuyer G, Wallner O, Müller S, Pham T, Göktürk C, Rasti A, Suman S, Torres-Ruiz R, Sarno A, Wiita E, Homan EJ, Karsten S, Marimuthu K, Michel M, Koolmeister T, Scobie M, Loseva O, Almlöf I, Unterlass JE, Pettke A, Boström J, Pandey M, Gad H, Herr P, Jemth AS, El Andaloussi S, Kalderén C, Rodriguez-Perales S, Benítez J, Krokan HE, Altun M, Stenmark P, Berglund UW, Helleday T. Visnes T, et al. Among authors: benitez j, benitez buelga c. Nucleic Acids Res. 2020 Dec 2;48(21):12234-12251. doi: 10.1093/nar/gkaa1048. Nucleic Acids Res. 2020. PMID: 33211885 Free PMC article.
A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers.
Baquero JM, Benítez-Buelga C, Fernández V, Urioste M, García-Giménez JL, Perona R; CIMBA Consortium; Benítez J, Osorio A. Baquero JM, et al. Among authors: benitez j, benitez buelga c. Mol Oncol. 2019 May;13(5):1110-1120. doi: 10.1002/1878-0261.12470. Epub 2019 Mar 1. Mol Oncol. 2019. PMID: 30747491 Free PMC article.
Small molecule inhibitor of OGG1 blocks oxidative DNA damage repair at telomeres and potentiates methotrexate anticancer effects.
Baquero JM, Benítez-Buelga C, Rajagopal V, Zhenjun Z, Torres-Ruiz R, Müller S, Hanna BMF, Loseva O, Wallner O, Michel M, Rodríguez-Perales S, Gad H, Visnes T, Helleday T, Benítez J, Osorio A. Baquero JM, et al. Among authors: benitez j, benitez buelga c. Sci Rep. 2021 Feb 10;11(1):3490. doi: 10.1038/s41598-021-82917-7. Sci Rep. 2021. PMID: 33568707 Free PMC article.
Alterations in SLC4A2, SLC26A7 and SLC26A9 Drive Acid-Base Imbalance in Gastric Neuroendocrine Tumors and Uncover a Novel Mechanism for a Co-Occurring Polyautoimmune Scenario.
Calvete O, Reyes J, Valdés-Socin H, Martin P, Marazuela M, Barroso A, Escalada J, Castells A, Torres-Ruiz R, Rodríguez-Perales S, Currás-Freixes M, Benítez J. Calvete O, et al. Among authors: benitez j. Cells. 2021 Dec 10;10(12):3500. doi: 10.3390/cells10123500. Cells. 2021. PMID: 34944008 Free PMC article.
OGG1 Inhibition Triggers Synthetic Lethality and Enhances The Effect of PARP Inhibitor Olaparib in BRCA1-Deficient TNBC Cells.
Baquero JM, Marchena-Perea E, Mirabet R, Torres-Ruiz R, Blanco-Aparicio C, Rodríguez-Perales S, Helleday T, Benítez-Buelga C, Benítez J, Osorio A. Baquero JM, et al. Among authors: benitez j, benitez buelga c. Front Oncol. 2022 May 10;12:888810. doi: 10.3389/fonc.2022.888810. eCollection 2022. Front Oncol. 2022. PMID: 35619904 Free PMC article.
Molecular cytogenetic characterization of rhabdomyosarcoma cell lines.
Rodriguez-Perales S, Martínez-Ramírez A, de Andrés SA, Valle L, Urioste M, Benítez J, Cigudosa JC. Rodriguez-Perales S, et al. Among authors: benitez j. Cancer Genet Cytogenet. 2004 Jan 1;148(1):35-43. doi: 10.1016/s0165-4608(03)00216-4. Cancer Genet Cytogenet. 2004. PMID: 14697639
Cloning of a new familial t(3;8) translocation associated with conventional renal cell carcinoma reveals a 5 kb microdeletion and no gene involved in the rearrangement.
Rodríguez-Perales S, Meléndez B, Gribble SM, Valle L, Carter NP, Santamaría I, Conde L, Urioste M, Benítez J, Cigudosa JC. Rodríguez-Perales S, et al. Among authors: benitez j. Hum Mol Genet. 2004 May 1;13(9):983-90. doi: 10.1093/hmg/ddh111. Epub 2004 Mar 11. Hum Mol Genet. 2004. PMID: 15016767
1,641 results