Chase A - Search Results

1

Pathogenic variants causing ABL1 malformation syndrome cluster in a myristoyl-binding pocket and increase tyrosine kinase activity.

Blakes AJM, Gaul E, Lam W, Shannon N, Knapp KM, Bicknell LS, Jackson MR, Wade EM, Robertson S, White SM, Heller R, Chase A, Baralle D, Douglas AGL. Blakes AJM, et al. Among authors: chase a. Eur J Hum Genet. 2021 Apr;29(4):593-603. doi: 10.1038/s41431-020-00766-w. Epub 2020 Nov 22. Eur J Hum Genet. 2021. PMID: 33223528 Free PMC article.

2

Genome-wide association study identifies novel susceptibility loci for KIT D816V positive mastocytosis.

Galatà G, García-Montero AC, Kristensen T, Dawoud AAZ, Muñoz-González JI, Meggendorfer M, Guglielmelli P, Hoade Y, Alvarez-Twose I, Gieger C, Strauch K, Ferrucci L, Tanaka T, Bandinelli S, Schnurr TM, Haferlach T, Broesby-Olsen S, Vestergaard H, Møller MB, Bindslev-Jensen C, Vannucchi AM, Orfao A, Radia D, Reiter A, Chase AJ, Cross NCP, Tapper WJ. Galatà G, et al. Among authors: chase aj. Am J Hum Genet. 2021 Feb 4;108(2):284-294. doi: 10.1016/j.ajhg.2020.12.007. Epub 2021 Jan 8. Am J Hum Genet. 2021. PMID: 33421400 Free PMC article.

3

A constitutively active SPTBN1-FLT3 fusion in atypical chronic myeloid leukemia is sensitive to tyrosine kinase inhibitors and immunotherapy.

Grand FH, Iqbal S, Zhang L, Russell NH, Chase A, Cross NC. Grand FH, et al. Among authors: chase a. Exp Hematol. 2007 Nov;35(11):1723-7. doi: 10.1016/j.exphem.2007.07.002. Epub 2007 Aug 30. Exp Hematol. 2007. PMID: 17764812 Free article.

4

Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders.

Ernst T, Chase AJ, Score J, Hidalgo-Curtis CE, Bryant C, Jones AV, Waghorn K, Zoi K, Ross FM, Reiter A, Hochhaus A, Drexler HG, Duncombe A, Cervantes F, Oscier D, Boultwood J, Grand FH, Cross NC. Ernst T, et al. Among authors: chase aj. Nat Genet. 2010 Aug;42(8):722-6. doi: 10.1038/ng.621. Epub 2010 Jul 4. Nat Genet. 2010. PMID: 20601953

5

Signal transduction therapy in haematological malignancies: identification and targeting of tyrosine kinases.

Chase A, Cross NC. Chase A, et al. Clin Sci (Lond). 2006 Oct;111(4):233-49. doi: 10.1042/CS20060035. Clin Sci (Lond). 2006. PMID: 16961463 Review.

6

Imatinib sensitivity as a consequence of a CSF1R-Y571D mutation and CSF1/CSF1R signaling abnormalities in the cell line GDM1.

Chase A, Schultheis B, Kreil S, Baxter J, Hidalgo-Curtis C, Jones A, Zhang L, Grand FH, Melo JV, Cross NC. Chase A, et al. Leukemia. 2009 Feb;23(2):358-64. doi: 10.1038/leu.2008.295. Epub 2008 Oct 30. Leukemia. 2009. PMID: 18971950

7

Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome.

Chase A, Grand FH, Cross NC. Chase A, et al. Blood. 2007 Nov 15;110(10):3729-34. doi: 10.1182/blood-2007-02-074286. Epub 2007 Aug 13. Blood. 2007. PMID: 17698633 Free article.

8

Heterogeneous prognostic impact of derivative chromosome 9 deletions in chronic myelogenous leukemia.

Kreil S, Pfirrmann M, Haferlach C, Waghorn K, Chase A, Hehlmann R, Reiter A, Hochhaus A, Cross NC; German Chronic Myelogenous Leukemia (CML) Study Group. Kreil S, et al. Among authors: chase a. Blood. 2007 Aug 15;110(4):1283-90. doi: 10.1182/blood-2007-02-074252. Epub 2007 Apr 24. Blood. 2007. PMID: 17456720 Free article.

9

JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms.

Jones AV, Chase A, Silver RT, Oscier D, Zoi K, Wang YL, Cario H, Pahl HL, Collins A, Reiter A, Grand F, Cross NC. Jones AV, et al. Among authors: chase a. Nat Genet. 2009 Apr;41(4):446-9. doi: 10.1038/ng.334. Epub 2009 Mar 15. Nat Genet. 2009. PMID: 19287382 Free PMC article.

10

Fusion of PDGFRB to two distinct loci at 3p21 and a third at 12q13 in imatinib-responsive myeloproliferative neoplasms.

Hidalgo-Curtis C, Apperley JF, Stark A, Jeng M, Gotlib J, Chase A, Cross NC, Grand FH. Hidalgo-Curtis C, et al. Among authors: chase a. Br J Haematol. 2010 Jan;148(2):268-73. doi: 10.1111/j.1365-2141.2009.07955.x. Br J Haematol. 2010. PMID: 20085582 Free article.

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