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162 results

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Effect of Ezogabine on Cortical and Spinal Motor Neuron Excitability in Amyotrophic Lateral Sclerosis: A Randomized Clinical Trial.
Wainger BJ, Macklin EA, Vucic S, McIlduff CE, Paganoni S, Maragakis NJ, Bedlack R, Goyal NA, Rutkove SB, Lange DJ, Rivner MH, Goutman SA, Ladha SS, Mauricio EA, Baloh RH, Simmons Z, Pothier L, Kassis SB, La T, Hall M, Evora A, Klements D, Hurtado A, Pereira JD, Koh J, Celnik PA, Chaudhry V, Gable K, Juel VC, Phielipp N, Marei A, Rosenquist P, Meehan S, Oskarsson B, Lewis RA, Kaur D, Kiskinis E, Woolf CJ, Eggan K, Weiss MD, Berry JD, David WS, Davila-Perez P, Camprodon JA, Pascual-Leone A, Kiernan MC, Shefner JM, Atassi N, Cudkowicz ME. Wainger BJ, et al. Among authors: eggan k. JAMA Neurol. 2021 Feb 1;78(2):186-196. doi: 10.1001/jamaneurol.2020.4300. JAMA Neurol. 2021. PMID: 33226425 Free PMC article. Clinical Trial.
Econazole selectively induces cell death in NF1-homozygous mutant tumor cells.
Lakes YB, Moye SL, Mo J, Tegtmeyer M, Nehme R, Charlton M, Salinas G, McKay RM, Eggan K, Le LQ. Lakes YB, et al. Among authors: eggan k. Cell Rep Med. 2023 Dec 19;4(12):101309. doi: 10.1016/j.xcrm.2023.101309. Epub 2023 Dec 11. Cell Rep Med. 2023. PMID: 38086379 Free PMC article.
Erosion of dosage compensation impacts human iPSC disease modeling.
Mekhoubad S, Bock C, de Boer AS, Kiskinis E, Meissner A, Eggan K. Mekhoubad S, et al. Among authors: eggan k. Cell Stem Cell. 2012 May 4;10(5):595-609. doi: 10.1016/j.stem.2012.02.014. Cell Stem Cell. 2012. PMID: 22560080 Free PMC article.
CLP1 links tRNA metabolism to progressive motor-neuron loss.
Hanada T, Weitzer S, Mair B, Bernreuther C, Wainger BJ, Ichida J, Hanada R, Orthofer M, Cronin SJ, Komnenovic V, Minis A, Sato F, Mimata H, Yoshimura A, Tamir I, Rainer J, Kofler R, Yaron A, Eggan KC, Woolf CJ, Glatzel M, Herbst R, Martinez J, Penninger JM. Hanada T, et al. Nature. 2013 Mar 28;495(7442):474-80. doi: 10.1038/nature11923. Epub 2013 Mar 10. Nature. 2013. PMID: 23474986 Free PMC article.
How to make spinal motor neurons.
Davis-Dusenbery BN, Williams LA, Klim JR, Eggan K. Davis-Dusenbery BN, et al. Among authors: eggan k. Development. 2014 Feb;141(3):491-501. doi: 10.1242/dev.097410. Development. 2014. PMID: 24449832 Review.
Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations.
Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SSW, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A, Clare AJ, Badders NM, Bilican B, Chaum E, Chandran S, Shaw CE, Eggan KC, Maniatis T, Taylor JP. Alami NH, et al. Neuron. 2014 Feb 5;81(3):536-543. doi: 10.1016/j.neuron.2013.12.018. Neuron. 2014. PMID: 24507191 Free PMC article.
162 results