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A comprehensive library of human transcription factors for cell fate engineering.
Ng AHM, Khoshakhlagh P, Rojo Arias JE, Pasquini G, Wang K, Swiersy A, Shipman SL, Appleton E, Kiaee K, Kohman RE, Vernet A, Dysart M, Leeper K, Saylor W, Huang JY, Graveline A, Taipale J, Hill DE, Vidal M, Melero-Martin JM, Busskamp V, Church GM. Ng AHM, et al. Among authors: taipale j. Nat Biotechnol. 2021 Apr;39(4):510-519. doi: 10.1038/s41587-020-0742-6. Epub 2020 Nov 30. Nat Biotechnol. 2021. PMID: 33257861 Free PMC article.
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.
Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, Jolma A, Steinmetz LM, Taipale J, Südhof TC, Wernig M. Mall M, et al. Among authors: taipale j. Nature. 2017 Apr 13;544(7649):245-249. doi: 10.1038/nature21722. Epub 2017 Apr 5. Nature. 2017. PMID: 28379941 Free article.
The interaction landscape between transcription factors and the nucleosome.
Zhu F, Farnung L, Kaasinen E, Sahu B, Yin Y, Wei B, Dodonova SO, Nitta KR, Morgunova E, Taipale M, Cramer P, Taipale J. Zhu F, et al. Among authors: taipale m, taipale j. Nature. 2018 Oct;562(7725):76-81. doi: 10.1038/s41586-018-0549-5. Epub 2018 Sep 24. Nature. 2018. PMID: 30250250 Free PMC article.
Systematic analysis of binding of transcription factors to noncoding variants.
Yan J, Qiu Y, Ribeiro Dos Santos AM, Yin Y, Li YE, Vinckier N, Nariai N, Benaglio P, Raman A, Li X, Fan S, Chiou J, Chen F, Frazer KA, Gaulton KJ, Sander M, Taipale J, Ren B. Yan J, et al. Among authors: taipale j. Nature. 2021 Mar;591(7848):147-151. doi: 10.1038/s41586-021-03211-0. Epub 2021 Jan 27. Nature. 2021. PMID: 33505025 Free PMC article.
Sequence determinants of human gene regulatory elements.
Sahu B, Hartonen T, Pihlajamaa P, Wei B, Dave K, Zhu F, Kaasinen E, Lidschreiber K, Lidschreiber M, Daub CO, Cramer P, Kivioja T, Taipale J. Sahu B, et al. Among authors: taipale j. Nat Genet. 2022 Mar;54(3):283-294. doi: 10.1038/s41588-021-01009-4. Epub 2022 Feb 21. Nat Genet. 2022. PMID: 35190730 Free PMC article.
DNA-binding specificities of human transcription factors.
Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. Jolma A, et al. Among authors: taipale m, taipale j. Cell. 2013 Jan 17;152(1-2):327-39. doi: 10.1016/j.cell.2012.12.009. Cell. 2013. PMID: 23332764 Free article.
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