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Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease.
Esrick EB, Lehmann LE, Biffi A, Achebe M, Brendel C, Ciuculescu MF, Daley H, MacKinnon B, Morris E, Federico A, Abriss D, Boardman K, Khelladi R, Shaw K, Negre H, Negre O, Nikiforow S, Ritz J, Pai SY, London WB, Dansereau C, Heeney MM, Armant M, Manis JP, Williams DA. Esrick EB, et al. Among authors: heeney mm. N Engl J Med. 2021 Jan 21;384(3):205-215. doi: 10.1056/NEJMoa2029392. Epub 2020 Dec 5. N Engl J Med. 2021. PMID: 33283990 Free PMC article. Clinical Trial.
Hydroxyurea for children with sickle cell disease.
Heeney MM, Ware RE. Heeney MM, et al. Pediatr Clin North Am. 2008 Apr;55(2):483-501, x. doi: 10.1016/j.pcl.2008.02.003. Pediatr Clin North Am. 2008. PMID: 18381097 Review.
A Multinational Trial of Prasugrel for Sickle Cell Vaso-Occlusive Events.
Heeney MM, Hoppe CC, Abboud MR, Inusa B, Kanter J, Ogutu B, Brown PB, Heath LE, Jakubowski JA, Zhou C, Zamoryakhin D, Agbenyega T, Colombatti R, Hassab HM, Nduba VN, Oyieko JN, Robitaille N, Segbefia CI, Rees DC; DOVE Investigators. Heeney MM, et al. N Engl J Med. 2016 Feb 18;374(7):625-35. doi: 10.1056/NEJMoa1512021. Epub 2015 Dec 8. N Engl J Med. 2016. PMID: 26644172 Free article. Clinical Trial.
Newborn Screening for Sickle Cell Disease in Liberia: A Pilot Study.
Tubman VN, Marshall R, Jallah W, Guo D, Ma C, Ohene-Frempong K, London WB, Heeney MM. Tubman VN, et al. Among authors: heeney mm. Pediatr Blood Cancer. 2016 Apr;63(4):671-6. doi: 10.1002/pbc.25875. Epub 2016 Jan 6. Pediatr Blood Cancer. 2016. PMID: 26739520 Free PMC article.
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim YJ, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. Brendel C, et al. Among authors: heeney mm. J Clin Invest. 2016 Oct 3;126(10):3868-3878. doi: 10.1172/JCI87885. Epub 2016 Sep 6. J Clin Invest. 2016. PMID: 27599293 Free PMC article.
Sickle Cell Disease.
Smith ER, Heeney M, Scott RM. Smith ER, et al. N Engl J Med. 2017 Jul 20;377(3):304. doi: 10.1056/NEJMc1706325. N Engl J Med. 2017. PMID: 28727407 Free article. No abstract available.
Randomized phase 2 trial of regadenoson for treatment of acute vaso-occlusive crises in sickle cell disease.
Field JJ, Majerus E, Gordeuk VR, Gowhari M, Hoppe C, Heeney MM, Achebe M, George A, Chu H, Sheehan B, Puligandla M, Neuberg D, Lin G, Linden J, Nathan DG. Field JJ, et al. Among authors: heeney mm. Blood Adv. 2017 Aug 28;1(20):1645-1649. doi: 10.1182/bloodadvances.2017009613. eCollection 2017 Sep 12. Blood Adv. 2017. PMID: 29296811 Free PMC article.
Normalizing hepcidin predicts TMPRSS6 mutation status in patients with chronic iron deficiency.
Heeney MM, Guo D, De Falco L, Campagna DR, Olbina G, Kao PP, Schmitz-Abe K, Rahimov F, Gutschow P, Westerman K, Ostland V, Jackson T, Klaassen RJ, Markianos K, Finberg KE, Iolascon A, Westerman M, London WB, Fleming MD. Heeney MM, et al. Blood. 2018 Jul 26;132(4):448-452. doi: 10.1182/blood-2017-03-773028. Epub 2018 Jun 12. Blood. 2018. PMID: 29895660 Free PMC article. No abstract available.
95 results