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Nanoscale imaging of RNA with expansion microscopy.
Chen F, Wassie AT, Cote AJ, Sinha A, Alon S, Asano S, Daugharthy ER, Chang JB, Marblestone A, Church GM, Raj A, Boyden ES. Chen F, et al. Nat Methods. 2016 Aug;13(8):679-84. doi: 10.1038/nmeth.3899. Epub 2016 Jul 4. Nat Methods. 2016. PMID: 27376770 Free PMC article.
Disease-associated astrocytes in Alzheimer's disease and aging.
Habib N, McCabe C, Medina S, Varshavsky M, Kitsberg D, Dvir-Szternfeld R, Green G, Dionne D, Nguyen L, Marshall JL, Chen F, Zhang F, Kaplan T, Regev A, Schwartz M. Habib N, et al. Among authors: chen f. Nat Neurosci. 2020 Jun;23(6):701-706. doi: 10.1038/s41593-020-0624-8. Epub 2020 Apr 27. Nat Neurosci. 2020. PMID: 32341542 Free PMC article.
Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling.
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D, Getz G, Boland GM, Chen F, Buenrostro JD, Hacohen N, Wu CJ, Aryee MJ, Regev A, Sankaran VG. Lareau CA, et al. Among authors: chen f. Nat Biotechnol. 2021 Apr;39(4):451-461. doi: 10.1038/s41587-020-0645-6. Epub 2020 Aug 12. Nat Biotechnol. 2021. PMID: 32788668 Free PMC article.
RNA timestamps identify the age of single molecules in RNA sequencing.
Rodriques SG, Chen LM, Liu S, Zhong ED, Scherrer JR, Boyden ES, Chen F. Rodriques SG, et al. Among authors: chen lm, chen f. Nat Biotechnol. 2021 Mar;39(3):320-325. doi: 10.1038/s41587-020-0704-z. Epub 2020 Oct 19. Nat Biotechnol. 2021. PMID: 33077959 Free PMC article.
HyPR-seq: Single-cell quantification of chosen RNAs via hybridization and sequencing of DNA probes.
Marshall JL, Doughty BR, Subramanian V, Guckelberger P, Wang Q, Chen LM, Rodriques SG, Zhang K, Fulco CP, Nasser J, Grinkevich EJ, Noel T, Mangiameli S, Bergman DT, Greka A, Lander ES, Chen F, Engreitz JM. Marshall JL, et al. Among authors: chen lm, chen f. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33404-33413. doi: 10.1073/pnas.2010738117. Epub 2020 Dec 21. Proc Natl Acad Sci U S A. 2020. PMID: 33376219 Free PMC article.
In situ genome sequencing resolves DNA sequence and structure in intact biological samples.
Payne AC, Chiang ZD, Reginato PL, Mangiameli SM, Murray EM, Yao CC, Markoulaki S, Earl AS, Labade AS, Jaenisch R, Church GM, Boyden ES, Buenrostro JD, Chen F. Payne AC, et al. Among authors: chen f. Science. 2021 Feb 26;371(6532):eaay3446. doi: 10.1126/science.aay3446. Epub 2020 Dec 31. Science. 2021. PMID: 33384301 Free PMC article.
Targeting a Braf/Mapk pathway rescues podocyte lipid peroxidation in CoQ-deficiency kidney disease.
Sidhom EH, Kim C, Kost-Alimova M, Ting MT, Keller K, Avila-Pacheco J, Watts AJ, Vernon KA, Marshall JL, Reyes-Bricio E, Racette M, Wieder N, Kleiner G, Grinkevich EJ, Chen F, Weins A, Clish CB, Shaw JL, Quinzii CM, Greka A. Sidhom EH, et al. Among authors: chen f. J Clin Invest. 2021 Mar 1;131(5):e141380. doi: 10.1172/JCI141380. J Clin Invest. 2021. PMID: 33444290 Free PMC article.
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