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Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture.
Nature. 2021 Jan;589(7841):299-305. doi: 10.1038/s41586-020-3017-y. Epub 2020 Dec 9.
Nature. 2021.
PMID: 33299181
Free PMC article.
H1 histones control the epigenetic landscape by local chromatin compaction.
Willcockson MA, Healton SE, Weiss CN, Bartholdy BA, Botbol Y, Mishra LN, Sidhwani DS, Wilson TJ, Pinto HB, Maron MI, Skalina KA, Toro LN, Zhao J, Lee CH, Hou H, Yusufova N, Meydan C, Osunsade A, David Y, Cesarman E, Melnick AM, Sidoli S, Garcia BA, Edelmann W, Macian F, Skoultchi AI.
Willcockson MA, et al. Among authors: osunsade a.
Nature. 2021 Jan;589(7841):293-298. doi: 10.1038/s41586-020-3032-z. Epub 2020 Dec 9.
Nature. 2021.
PMID: 33299182
Free PMC article.
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Reversible histone glycation is associated with disease-related changes in chromatin architecture.
Zheng Q, Omans ND, Leicher R, Osunsade A, Agustinus AS, Finkin-Groner E, D'Ambrosio H, Liu B, Chandarlapaty S, Liu S, David Y.
Zheng Q, et al. Among authors: osunsade a.
Nat Commun. 2019 Mar 20;10(1):1289. doi: 10.1038/s41467-019-09192-z.
Nat Commun. 2019.
PMID: 30894531
Free PMC article.
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Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation.
Zheng Q, Osunsade A, David Y.
Zheng Q, et al. Among authors: osunsade a.
Nat Commun. 2020 Jun 26;11(1):3241. doi: 10.1038/s41467-020-17066-y.
Nat Commun. 2020.
PMID: 32591537
Free PMC article.
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Single-stranded nucleic acid binding and coacervation by linker histone H1.
Leicher R, Osunsade A, Chua GNL, Faulkner SC, Latham AP, Watters JW, Nguyen T, Beckwitt EC, Christodoulou-Rubalcava S, Young PG, Zhang B, David Y, Liu S.
Leicher R, et al. Among authors: osunsade a.
Nat Struct Mol Biol. 2022 May;29(5):463-471. doi: 10.1038/s41594-022-00760-4. Epub 2022 Apr 28.
Nat Struct Mol Biol. 2022.
PMID: 35484234
Free PMC article.
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Chromatin sequesters pioneer transcription factor Sox2 from exerting force on DNA.
Nguyen T, Li S, Chang JT, Watters JW, Ng H, Osunsade A, David Y, Liu S.
Nguyen T, et al. Among authors: osunsade a.
Nat Commun. 2022 Jul 9;13(1):3988. doi: 10.1038/s41467-022-31738-x.
Nat Commun. 2022.
PMID: 35810158
Free PMC article.
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A Robust Method for the Purification and Characterization of Recombinant Human Histone H1 Variants.
Osunsade A, Prescott NA, Hebert JM, Ray DM, Jmeian Y, Lorenz IC, David Y.
Osunsade A, et al.
Biochemistry. 2019 Jan 22;58(3):171-176. doi: 10.1021/acs.biochem.8b01060. Epub 2019 Jan 8.
Biochemistry. 2019.
PMID: 30585724
Free PMC article.
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