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A cell competition-based small molecule screen identifies a novel compound that induces dual c-Myc depletion and p53 activation.
Tadele DS, Robertson J, Crispin R, Herrera MC, Chlubnová M, Piechaczyk L, Ayuda-Durán P, Singh SK, Gedde-Dahl T, Fløisand Y, Skavland J, Wesche J, Gjertsen BT, Enserink JM. Tadele DS, et al. Among authors: enserink jm. J Biol Chem. 2021 Jan-Jun;296:100179. doi: 10.1074/jbc.RA120.015285. Epub 2020 Dec 17. J Biol Chem. 2021. PMID: 33303632 Free PMC article.
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors.
Pietarinen PO, Eide CA, Ayuda-Durán P, Potdar S, Kuusanmäki H, Andersson EI, Mpindi JP, Pemovska T, Kontro M, Heckman CA, Kallioniemi O, Wennerberg K, Hjorth-Hansen H, Druker BJ, Enserink JM, Tyner JW, Mustjoki S, Porkka K. Pietarinen PO, et al. Among authors: enserink jm. Oncotarget. 2017 Apr 4;8(14):22606-22615. doi: 10.18632/oncotarget.15146. Oncotarget. 2017. PMID: 28186983 Free PMC article.
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells.
Zhang B, Durán PA, Piechaczyk L, Fløisand Y, Safont MMS, Karlsen IT, Fandalyuk Z, Tadele D, Mierlo PV, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM; Bjørn Tore Gjertsen Group; Emmet McCormack Group. Zhang B, et al. Among authors: enserink jm. Haematologica. 2018 May 10;Online ahead of print. doi: 10.3324/haematol.2018.189399. Online ahead of print. Haematologica. 2018. PMID: 29748445 Free article. Retracted.
GRP94 rewires and buffers the FLT3-ITD signaling network and promotes survival of acute myeloid leukemic stem cells.
Zhang B, Ayuda-Durán P, Piechaczyk L, Fløisand Y, Safont MM, Karlsen IT, Fandalyuk Z, Tadele D, van Mierlo P, Rowe AD, Robertson JM, Gjertsen BT, McCormack E, Enserink JM. Zhang B, et al. Among authors: enserink jm. Haematologica. 2019 May;104(5):e229. doi: 10.3324/haematol.2019.220533. Haematologica. 2019. PMID: 31040234 Free PMC article. No abstract available.
69 results