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A Novel Biomarker of Neuronal Glutamate Metabolism in Nonhuman Primates Using Localized 1H-Magnetic Resonance Spectroscopy: Development and Effects of BNC375, an α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator.
Miller CO, Gantert LT, Previs SF, Chen Y, Anderson KD, Thomas JM, Sanacora G, Uslaner JM, Rothman DL, Mason GF. Miller CO, et al. Among authors: chen y. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Jun;7(6):598-606. doi: 10.1016/j.bpsc.2020.09.014. Epub 2020 Sep 29. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022. PMID: 33309567 Free PMC article.
Quantifying rates of glucose production in vivo following an intraperitoneal tracer bolus.
Wang SP, Zhou D, Yao Z, Satapati S, Chen Y, Daurio NA, Petrov A, Shen X, Metzger D, Yin W, Nawrocki AR, Eiermann GJ, Hwa J, Fancourt C, Miller C, Herath K, Roddy TP, Slipetz D, Erion MD, Previs SF, Kelley DE. Wang SP, et al. Among authors: chen y. Am J Physiol Endocrinol Metab. 2016 Dec 1;311(6):E911-E921. doi: 10.1152/ajpendo.00182.2016. Epub 2016 Sep 20. Am J Physiol Endocrinol Metab. 2016. PMID: 27651111 Free article.
Effects of anacetrapib on plasma lipids, apolipoproteins and PCSK9 in healthy, lean rhesus macaques.
Roddy TP, McLaren DG, Chen Y, Xie D, Dunn K, Kulick A, Szeto D, Forrest G, Albanese K, Donnelly M, Gai C, Gewain A, Lederman H, Jensen KK, Ai X, Vachal P, Akinsanya KO, Cleary MA, Previs SF, Dansky HM, Johns DG. Roddy TP, et al. Among authors: chen y. Eur J Pharmacol. 2014 Oct 5;740:410-6. doi: 10.1016/j.ejphar.2014.04.015. Epub 2014 Apr 21. Eur J Pharmacol. 2014. PMID: 24769414
Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS.
Pan Y, Zhou H, Mahsut A, Rohm RJ, Berejnaia O, Price O, Chen Y, Castro-Perez J, Lassman ME, McLaren D, Conway J, Jensen KK, Thomas T, Reyes-Soffer G, Ginsberg HN, Gutstein DE, Cleary M, Previs SF, Roddy TP. Pan Y, et al. Among authors: chen y. J Lipid Res. 2014 Jun;55(6):1179-87. doi: 10.1194/jlr.D047829. Epub 2014 Apr 2. J Lipid Res. 2014. PMID: 24694356 Free PMC article.
Phenotyping of adipose, liver, and skeletal muscle insulin resistance and response to pioglitazone in spontaneously obese rhesus monkeys.
Shang J, Previs SF, Conarello S, Chng K, Zhu Y, Souza SC, Staup M, Chen Y, Xie D, Zycband E, Schlessinger K, Johnson VP, Arreaza G, Liu F, Levitan D, Wang L, van Heek M, Erion M, Wang Y, Kelley DE. Shang J, et al. Among authors: chen y. Am J Physiol Endocrinol Metab. 2017 Apr 1;312(4):E235-E243. doi: 10.1152/ajpendo.00398.2016. Epub 2017 Jan 31. Am J Physiol Endocrinol Metab. 2017. PMID: 28143858 Free article.
Quantifying ceramide kinetics in vivo using stable isotope tracers and LC-MS/MS.
Chen Y, Berejnaia O, Liu J, Wang SP, Daurio NA, Yin W, Mayoral R, Petrov A, Kasumov T, Zhang GF, Previs SF, Kelley DE, McLaren DG. Chen Y, et al. Am J Physiol Endocrinol Metab. 2018 Sep 1;315(3):E416-E424. doi: 10.1152/ajpendo.00457.2017. Epub 2018 Mar 6. Am J Physiol Endocrinol Metab. 2018. PMID: 29509438 Free article.
Enhancing Studies of Pharmacodynamic Mechanisms via Measurements of Metabolic Flux: Fundamental Concepts and Guiding Principles for Using Stable Isotope Tracers.
Daurio NA, Wang SP, Chen Y, Zhou H, McLaren DG, Roddy TP, Johns DG, Milot D, Kasumov T, Erion MD, Kelley DE, Previs SF. Daurio NA, et al. Among authors: chen y. J Pharmacol Exp Ther. 2017 Oct;363(1):80-91. doi: 10.1124/jpet.117.241091. Epub 2017 Jul 19. J Pharmacol Exp Ther. 2017. PMID: 28724692 Review.
Spatial and temporal studies of metabolic activity: contrasting biochemical kinetics in tissues and pathways during fasted and fed states.
Daurio NA, Wang Y, Chen Y, Zhou H, Carballo-Jane E, Mane J, Rodriguez CG, Zafian P, Houghton A, Addona G, McLaren DG, Zhang R, Shyong BJ, Bateman K, Downes DP, Webb M, Kelley DE, Previs SF. Daurio NA, et al. Among authors: chen y. Am J Physiol Endocrinol Metab. 2019 Jun 1;316(6):E1105-E1117. doi: 10.1152/ajpendo.00459.2018. Epub 2019 Mar 26. Am J Physiol Endocrinol Metab. 2019. PMID: 30912961 Free article.
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