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Kinomic profiling of tumour xenografts derived from patients with non-small cell lung cancer confirms their fidelity and reveals potentially actionable pathways.
Tabbò F, Guerrera F, van den Berg A, Gaudiano M, Maletta F, Bessone L, Nottegar A, Costardi L, de Wijn R, Ruijtenbeek R, Delsedime L, Sapino A, Ruffini E, Hilhorst R, Inghirami G. Tabbò F, et al. Among authors: sapino a. Eur J Cancer. 2021 Feb;144:17-30. doi: 10.1016/j.ejca.2020.10.036. Epub 2020 Dec 11. Eur J Cancer. 2021. PMID: 33316635
A molecularly annotated platform of patient-derived xenografts ("xenopatients") identifies HER2 as an effective therapeutic target in cetuximab-resistant colorectal cancer.
Bertotti A, Migliardi G, Galimi F, Sassi F, Torti D, Isella C, Corà D, Di Nicolantonio F, Buscarino M, Petti C, Ribero D, Russolillo N, Muratore A, Massucco P, Pisacane A, Molinaro L, Valtorta E, Sartore-Bianchi A, Risio M, Capussotti L, Gambacorta M, Siena S, Medico E, Sapino A, Marsoni S, Comoglio PM, Bardelli A, Trusolino L. Bertotti A, et al. Among authors: sapino a. Cancer Discov. 2011 Nov;1(6):508-23. doi: 10.1158/2159-8290.CD-11-0109. Epub 2011 Sep 2. Cancer Discov. 2011. PMID: 22586653 Free article.
Gene status in HER2 equivocal breast carcinomas: impact of distinct recommendations and contribution of a polymerase chain reaction-based method.
Sapino A, Maletta F, Verdun di Cantogno L, Macrì L, Botta C, Gugliotta P, Scalzo MS, Annaratone L, Balmativola D, Pietribiasi F, Bernardi P, Arisio R, Viberti L, Guzzetti S, Orlassino R, Ercolani C, Mottolese M, Viale G, Marchiò C. Sapino A, et al. Oncologist. 2014 Nov;19(11):1118-26. doi: 10.1634/theoncologist.2014-0195. Epub 2014 Oct 16. Oncologist. 2014. PMID: 25323485 Free PMC article.
Pathological non-response to chemotherapy in a neoadjuvant setting of breast cancer: an inter-institutional study.
Balmativola D, Marchiò C, Maule M, Chiusa L, Annaratone L, Maletta F, Montemurro F, Kulka J, Figueiredo P, Varga Z, Liepniece-Karele I, Cserni G, Arkoumani E, Amendoeira I, Callagy G, Reiner-Concin A, Cordoba A, Bianchi S, Decker T, Gläser D, Focke C, van Diest P, Grabau D, Lips E, Wesseling J, Arisio R, Medico E, Wells C, Sapino A. Balmativola D, et al. Among authors: sapino a. Breast Cancer Res Treat. 2014 Dec;148(3):511-23. doi: 10.1007/s10549-014-3192-3. Epub 2014 Nov 14. Breast Cancer Res Treat. 2014. PMID: 25395316 Free PMC article.
401 results