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Chi3l1/YKL-40 is controlled by the astrocyte circadian clock and regulates neuroinflammation and Alzheimer's disease pathogenesis.
Lananna BV, McKee CA, King MW, Del-Aguila JL, Dimitry JM, Farias FHG, Nadarajah CJ, Xiong DD, Guo C, Cammack AJ, Elias JA, Zhang J, Cruchaga C, Musiek ES. Lananna BV, et al. Among authors: elias ja. Sci Transl Med. 2020 Dec 16;12(574):eaax3519. doi: 10.1126/scitranslmed.aax3519. Sci Transl Med. 2020. PMID: 33328329 Free PMC article.
Chitinase 3-like 1 suppresses injury and promotes fibroproliferative responses in Mammalian lung fibrosis.
Zhou Y, Peng H, Sun H, Peng X, Tang C, Gan Y, Chen X, Mathur A, Hu B, Slade MD, Montgomery RR, Shaw AC, Homer RJ, White ES, Lee CM, Moore MW, Gulati M, Lee CG, Elias JA, Herzog EL. Zhou Y, et al. Among authors: elias ja. Sci Transl Med. 2014 Jun 11;6(240):240ra76. doi: 10.1126/scitranslmed.3007096. Sci Transl Med. 2014. PMID: 24920662 Free PMC article.
Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF Jr, Nicolae DL, Elias JA, Chupp GL. Ober C, et al. Among authors: elias ja. N Engl J Med. 2008 Apr 17;358(16):1682-91. doi: 10.1056/NEJMoa0708801. Epub 2008 Apr 9. N Engl J Med. 2008. PMID: 18403759 Free PMC article.
319 results